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A framework for designing delivery systems
The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …
and treating patients. Nanomaterials are promising vehicles to transport agents that include …
[HTML][HTML] The multifaceted roles of copper in cancer: A trace metal element with dysregulated metabolism, but also a target or a bullet for therapy
Simple Summary Copper is an essential element for human life. However, its redox activity
can be detrimental for the cell that developed highly coordinated pathways to chelate and …
can be detrimental for the cell that developed highly coordinated pathways to chelate and …
Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …
Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …
[HTML][HTML] Enhanced permeability and retention effect as a ubiquitous and epoch-making phenomenon for the selective drug targeting of solid tumors
In 1979, development of the first polymer drug SMANCS [styrene-co-maleic acid (SMA)
copolymer conjugated to neocarzinostatin (NCS)] by Maeda and colleagues was a …
copolymer conjugated to neocarzinostatin (NCS)] by Maeda and colleagues was a …
[HTML][HTML] Nanomedicine in pancreatic cancer: current status and future opportunities for overcoming therapy resistance
MK Greene, MC Johnston, CJ Scott - Cancers, 2021 - mdpi.com
Simple Summary Despite access to a vast arsenal of anticancer agents, many fail to realise
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …
Recent research progress of RGD peptide–modified nanodrug delivery systems in tumor therapy
L Yin, X Li, R Wang, Y Zeng, Z Zeng, T **e - International Journal of …, 2023 - Springer
There have been great advancements in targeted nanodrug delivery systems for tumor
therapy. Liposomes, polymeric nanoparticles, and inorganic nanoparticles are commonly …
therapy. Liposomes, polymeric nanoparticles, and inorganic nanoparticles are commonly …
[HTML][HTML] Localized nanotheranostics: recent developments in cancer nanomedicine
Since decades, conventional diagnosis and treatment strategies for cancer have been
practiced widely despite their expensive and time-consuming process. These conventional …
practiced widely despite their expensive and time-consuming process. These conventional …
CT and MRI Imaging of Theranostic Bimodal Fe3O4@Au NanoParticles in Tumor Bearing Mice
AA Lipengolts, YA Finogenova, VA Skribitsky… - International Journal of …, 2022 - mdpi.com
Gold-containing nanoparticles are proven to be an effective radiosensitizer in the
radiotherapy of tumors. Reliable imaging of nanoparticles in a tumor and surrounding …
radiotherapy of tumors. Reliable imaging of nanoparticles in a tumor and surrounding …
Modeling physical forces experienced by cancer and stromal cells within different organ-specific tumor tissue
M Connaughton, M Dabagh - IEEE Journal of Translational …, 2024 - ieeexplore.ieee.org
Mechanical force exerted on cancer cells by their microenvironment have been reported to
drive cells toward invasive phenotypes by altering cells' motility, proliferation, and apoptosis …
drive cells toward invasive phenotypes by altering cells' motility, proliferation, and apoptosis …