A framework for designing delivery systems

W Poon, BR Kingston, B Ouyang, W Ngo… - Nature …, 2020 - nature.com
The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

[HTML][HTML] The multifaceted roles of copper in cancer: A trace metal element with dysregulated metabolism, but also a target or a bullet for therapy

P Lelièvre, L Sancey, JL Coll, A Deniaud, B Busser - Cancers, 2020 - mdpi.com
Simple Summary Copper is an essential element for human life. However, its redox activity
can be detrimental for the cell that developed highly coordinated pathways to chelate and …

Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions

J Schuemann, AF Bagley, R Berbeco… - Physics in Medicine …, 2020 - iopscience.iop.org
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine

JA Damasco, S Ravi, JD Perez, DE Hagaman… - Nanomaterials, 2020 - mdpi.com
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …

[HTML][HTML] Enhanced permeability and retention effect as a ubiquitous and epoch-making phenomenon for the selective drug targeting of solid tumors

W Islam, T Niidome, T Sawa - Journal of Personalized Medicine, 2022 - mdpi.com
In 1979, development of the first polymer drug SMANCS [styrene-co-maleic acid (SMA)
copolymer conjugated to neocarzinostatin (NCS)] by Maeda and colleagues was a …

[HTML][HTML] Nanomedicine in pancreatic cancer: current status and future opportunities for overcoming therapy resistance

MK Greene, MC Johnston, CJ Scott - Cancers, 2021 - mdpi.com
Simple Summary Despite access to a vast arsenal of anticancer agents, many fail to realise
their full therapeutic potential in clinical practice. One key determinant of this is the evolution …

Recent research progress of RGD peptide–modified nanodrug delivery systems in tumor therapy

L Yin, X Li, R Wang, Y Zeng, Z Zeng, T **e - International Journal of …, 2023 - Springer
There have been great advancements in targeted nanodrug delivery systems for tumor
therapy. Liposomes, polymeric nanoparticles, and inorganic nanoparticles are commonly …

[HTML][HTML] Localized nanotheranostics: recent developments in cancer nanomedicine

R Prasad, NK Jain, J Conde, R Srivastava - Materials Today Advances, 2020 - Elsevier
Since decades, conventional diagnosis and treatment strategies for cancer have been
practiced widely despite their expensive and time-consuming process. These conventional …

CT and MRI Imaging of Theranostic Bimodal Fe3O4@Au NanoParticles in Tumor Bearing Mice

AA Lipengolts, YA Finogenova, VA Skribitsky… - International Journal of …, 2022 - mdpi.com
Gold-containing nanoparticles are proven to be an effective radiosensitizer in the
radiotherapy of tumors. Reliable imaging of nanoparticles in a tumor and surrounding …

Modeling physical forces experienced by cancer and stromal cells within different organ-specific tumor tissue

M Connaughton, M Dabagh - IEEE Journal of Translational …, 2024 - ieeexplore.ieee.org
Mechanical force exerted on cancer cells by their microenvironment have been reported to
drive cells toward invasive phenotypes by altering cells' motility, proliferation, and apoptosis …