Since its discovery as a primary component in cytoplasmic aggregates in post-mortem tissue
of patients with Amyotrophic Lateral Sclerosis (ALS), TAR DNA Binding Protein 43 kDa (TDP …

Cancer researchers have traditionally used the mouse and the rat as staple model
organisms. These animals are very short-lived, reproduce rapidly and are highly prone to …

Bacterial anti-phage systems are frequently clustered in microbial genomes, forming
defense islands. This property enabled the recent discovery of multiple defense systems …

Covalent triazine frameworks (CTFs) are normally synthesized by ionothermal methods. The
harsh synthetic conditions and associated limited structural diversity do not benefit for further …

Bats are special in their ability to live long and host many emerging viruses. Our previous
studies showed that bats have altered inflammasomes, which are central players in aging …

Dynamic covalent chemistry enables self-assembly of reactive building blocks into
structurally complex yet robust materials, such as covalent organic frameworks (COFs) …

Identifying the genomic changes that underlie phenotypic adaptations is a key challenge in
evolutionary biology and genomics. Loss of protein-coding genes is one type of genomic …

The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

Develo** highly efficient electrocatalysts for renewable energy conversion and
environment purification has long been a research priority in the past 15 years. Covalent …

Blind mole rats (BMRs) are small rodents, characterized by an exceptionally long lifespan (>
21 years) and resistance to both spontaneous and induced tumorigenesis. Here we report …