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[HTML][HTML] ncRNA-mediated ceRNA regulatory network: Transcriptomic insights into breast cancer progression and treatment strategies
S Yang, X Wang, X Zhou, L Hou, J Wu, W Zhang… - Biomedicine & …, 2023 - Elsevier
With the rapid development of next-generation sequencing technology, several studies have
shown that ncRNAs can act as competitive endogenous RNAs (ceRNAs) and are involved in …
shown that ncRNAs can act as competitive endogenous RNAs (ceRNAs) and are involved in …
Bioinspired Spatiotemporal Management toward RNA Therapies
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …
intervention, especially with some that have been approved by the FDA such as the mRNA …
A perspective of lipid nanoparticles for RNA delivery
Over the last two decades, lipid nanoparticles (LNPs) have evolved as an effective
biocompatible and biodegradable RNA delivery platform in the fields of nanomedicine …
biocompatible and biodegradable RNA delivery platform in the fields of nanomedicine …
Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea
M Wang, Y Dong, S Gao, Z Zhong, C Cheng… - Cellular and Molecular …, 2022 - Springer
Abstract The Hippo/Yes-associated protein (YAP) signaling pathway has been shown to be
able to maintain organ size and homeostasis by regulating cell proliferation, differentiation …
able to maintain organ size and homeostasis by regulating cell proliferation, differentiation …
Towards the translation of electroconductive organic materials for regeneration of neural tissues
Carbon-based conductive and electroactive materials (eg, derivatives of graphene,
fullerenes, polypyrrole, polythiophene, polyaniline) have been studied since the 1970s for …
fullerenes, polypyrrole, polythiophene, polyaniline) have been studied since the 1970s for …
[HTML][HTML] Noise induced hearing loss and tinnitus—new research developments and remaining gaps in disease assessment, treatment, and prevention
Long-term noise exposure often results in noise induced hearing loss (NIHL). Tinnitus, the
generation of phantom sounds, can also result from noise exposure, although …
generation of phantom sounds, can also result from noise exposure, although …
Estradiol protects against noise-induced hearing loss and modulates auditory physiology in female mice
Recent studies have identified sex-differences in auditory physiology and in the
susceptibility to noise-induced hearing loss (NIHL). We hypothesize that 17β-estradiol (E2) …
susceptibility to noise-induced hearing loss (NIHL). We hypothesize that 17β-estradiol (E2) …
Cochlear health and cochlear-implant function
KC Schvartz-Leyzac, DJ Colesa, DL Swiderski… - Journal of the …, 2023 - Springer
The cochlear implant (CI) is widely considered to be one of the most innovative and
successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are …
successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are …
The BDNF/TrkB neurotrophin system in the sensory organs of zebrafish
M Aragona, C Porcino, MC Guerrera… - International journal of …, 2022 - mdpi.com
The brain-derived neurotrophic factor (BDNF) was discovered in the last century, and
identified as a member of the neurotrophin family. BDNF shares approximately 50% of its …
identified as a member of the neurotrophin family. BDNF shares approximately 50% of its …
ROS-responsive nanoparticle as a berberine carrier for OHC-targeted therapy of noise-induced hearing loss
Z Zhao, Z Han, K Naveena, G Lei, S Qiu… - … applied materials & …, 2021 - ACS Publications
Overproduction of reactive oxygen species (ROS) and inflammation are two key
pathogeneses of noise-induced hearing loss (NIHL), which leads to outer hair cell (OHC) …
pathogeneses of noise-induced hearing loss (NIHL), which leads to outer hair cell (OHC) …