Behavioral control by depolarized and hyperpolarized states of an integrating neuron
A Sordillo, CI Bargmann - Elife, 2021 - elifesciences.org
Coordinated transitions between mutually exclusive motor states are central to behavioral
decisions. During locomotion, the nematode Caenorhabditis elegans spontaneously cycles …
decisions. During locomotion, the nematode Caenorhabditis elegans spontaneously cycles …
Hierarchical behavior control by a single class of interneurons
J Huo, T Xu, Q Liu, M Polat, S Kumar, X Zhang… - Proceedings of the …, 2024 - pnas.org
Animal behavior is organized into nested temporal patterns that span multiple timescales.
This behavior hierarchy is believed to arise from a hierarchical neural architecture: Neurons …
This behavior hierarchy is believed to arise from a hierarchical neural architecture: Neurons …
Inhibitory feedback from the motor circuit gates mechanosensory processing in Caenorhabditis elegans
Animals must integrate sensory cues with their current behavioral context to generate a
suitable response. How this integration occurs is poorly understood. Previously, we …
suitable response. How this integration occurs is poorly understood. Previously, we …
Integration of spatially opposing cues by a single interneuron guides decision-making in C. elegans
A Gat, V Pechuk, S Peedikayil-Kurien, S Karimi… - Cell Reports, 2023 - cell.com
The capacity of animals to respond to hazardous stimuli in their surroundings is crucial for
their survival. In mammals, complex evaluations of the environment require large numbers …
their survival. In mammals, complex evaluations of the environment require large numbers …
[HTML][HTML] Behavioral adjustment of C. elegans to mechanosensory loss requires intact mechanosensory neurons
M Staum, AC Abraham, R Arbid, VS Birari… - Plos …, 2024 - journals.plos.org
Sensory neurons specialize in detecting and signaling the presence of diverse
environmental stimuli. Neuronal injury or disease may undermine such signaling …
environmental stimuli. Neuronal injury or disease may undermine such signaling …
pOpsicle: An all-optical reporter system for synaptic vesicle recycling combining pH-sensitive fluorescent proteins with optogenetic manipulation of neuronal activity
M Seidenthal, B Jánosi, N Rosenkranz… - Frontiers in Cellular …, 2023 - frontiersin.org
pH-sensitive fluorescent proteins are widely used to study synaptic vesicle (SV) fusion and
recycling. When targeted to the lumen of SVs, fluorescence of these proteins is quenched by …
recycling. When targeted to the lumen of SVs, fluorescence of these proteins is quenched by …
Nervous system guides behavioral immunity in Caenorhabditis elegans
Y Wang, X Sun, L Feng, K Zhang, W Yang - PeerJ, 2024 - peerj.com
Caenorhabditis elegans is a versatile model organism for exploring complex biological
systems. Microbes and the external environment can affect the nervous system and drive …
systems. Microbes and the external environment can affect the nervous system and drive …
Olfactory combinatorial coding supports risk-reward decision making in C. elegans
Vertebrate and insect olfactory systems generate diversity in odor perception using
combinatorial coding, where individual odorant molecules activate unique but overlap** …
combinatorial coding, where individual odorant molecules activate unique but overlap** …
Coordinated electrical and chemical signaling between two neurons orchestrates switching of motor states
To survive in a complex environment, animals must respond to external cues, eg, to escape
threats or to navigate towards favorable locations. Navigating requires transition between …
threats or to navigate towards favorable locations. Navigating requires transition between …
pOpsicle: An all-optical reporter system for synaptic vesicle recycling combining pH-sensitive fluorescent proteins with optogenetic manipulation of neuronal activity
M Seidenthal, B Jánosi, N Rosenkranz, N Schuh… - bioRxiv, 2022 - biorxiv.org
Abstract pH-sensitive fluorescent proteins are widely used to study synaptic vesicle (SV)
fusion and recycling. When targeted to the lumen of SVs, fluorescence of these proteins is …
fusion and recycling. When targeted to the lumen of SVs, fluorescence of these proteins is …