Neutrophil diversity and plasticity in tumour progression and therapy
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …
Neutrophils as emerging therapeutic targets
Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
against bacterial and fungal infections. However, neutrophils also contribute to tissue …
Programmed 'disarming'of the neutrophil proteome reduces the magnitude of inflammation
JM Adrover, A Aroca-Crevillén, G Crainiciuc… - Nature …, 2020 - nature.com
The antimicrobial functions of neutrophils are facilitated by a defensive armamentarium of
proteins stored in granules, and by the formation of neutrophil extracellular traps (NETs) …
proteins stored in granules, and by the formation of neutrophil extracellular traps (NETs) …
Phagocytosis, degranulation and extracellular traps release by neutrophils—the current knowledge, pharmacological modulation and future prospects
B Gierlikowska, A Stachura, W Gierlikowski… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …
Mouse Models and Tools for the in vivo Study of Neutrophils
Neutrophils are the most abundant leukocytes in human blood and critical actors of the
immune system. Many neutrophil functions and facets of their activity in vivo were revealed …
immune system. Many neutrophil functions and facets of their activity in vivo were revealed …
Neutrophils in malaria: A double-edged sword role
KA Babatunde, OF Adenuga - Frontiers in immunology, 2022 - frontiersin.org
Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …
line of defense against invading foreign pathogens and might play a crucial role in malaria …
Neutrophil-derived granule cargoes: paving the way for tumor growth and progression
Neutrophils are the key cells of our innate immune system mediating host defense via a
range of effector functions including phagocytosis, degranulation, and NETosis. For this …
range of effector functions including phagocytosis, degranulation, and NETosis. For this …
A cardioimmunologist's toolkit: genetic tools to dissect immune cells in cardiac disease
A Wong, H Hamidzada, S Epelman - Nature Reviews Cardiology, 2022 - nature.com
Cardioimmunology is a field that encompasses the immune cells and pathways that
modulate cardiac function in homeostasis and regulate the temporal balance between tissue …
modulate cardiac function in homeostasis and regulate the temporal balance between tissue …
[HTML][HTML] Pseudomonas aeruginosa hijacks the murine nitric oxide metabolic pathway to evade killing by neutrophils in the lung
Neutrophils play a critical role in the eradication of Pseudomonas aeruginosa, a major
pathogen causing lung infection. However, the mechanisms used by the pathogen to evade …
pathogen causing lung infection. However, the mechanisms used by the pathogen to evade …
BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection
Neutrophils are vital for antimicrobial defense; however, their role during viral infection is
less clear. Furthermore, the molecular regulation of neutrophil fate and function at the viral …
less clear. Furthermore, the molecular regulation of neutrophil fate and function at the viral …