Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic disorder
associated with a severe deficiency of ADAMTS-13—the protease that cleaves von …

We investigated the contribution of human platelets to macrophage effector properties in the
presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for …

Cancer-associated adipocytes have functional roles in tumor development through secreted
adipocyte-derived factors and exosomes and also through metabolic symbiosis, where the …

Neutrophil NETosis is a unique form of cell death, characterized by the release of
decondensed chromatin and antimicrobial contents to the extracellular space, which is …

Fibrinolytics delivered into the general circulation lack selectivity for nascent thrombi,
reducing efficacy and increasing the risk of bleeding. Urokinase-type plasminogen activator …

Although procoagulant TF is clearly expressed in the vascular subendothelium, it has also
been proposed that many different cell types express an inactive, encrypted form of TF that …

Storage requirements and outdating of platelets represent a continued challenge for blood
banks. These hurdles are confounded for rural area hospitals or in military deployments …

Protease activity has been implicated in the pathogenesis of vascular diseases, including
atherosclerosis, thrombosis, and aneurysm. A wide variety of proteases representing …

Background Neutrophil NETosis and neutrophil extracellular traps (NETs) play a critical role
in pathogenesis of coronavirus disease 2019 (COVID-19)-associated thrombosis. However …

e160 Arterioscler Thromb Vasc Biol June 2019 we have tried to elucidate the pathogenesis
of this disorder. Importantly, plasma levels of TAFI (also known as carboxypeptidase B2 …