Image to insight: exploring natural products through mass spectrometry imaging
Covering: 2017 to 2022 Mass spectrometry imaging (MSI) has become a mature molecular
imaging technique that is well-matched for natural product (NP) discovery. Here we present …
imaging technique that is well-matched for natural product (NP) discovery. Here we present …
Organ evolution: emergence of multicellular function
J Parker - Annual Review of Cell and Developmental Biology, 2024 - annualreviews.org
Instances of multicellularity across the tree of life have fostered the evolution of complex
organs composed of distinct cell types that cooperate, producing emergent biological …
organs composed of distinct cell types that cooperate, producing emergent biological …
Mass spectrometry imaging of lipids with isomer resolution using high-pressure ozone-induced dissociation
Mass spectrometry imaging (MSI) of lipids within tissues has significant potential for both
biomolecular discovery and histopathological applications. Conventional MSI technologies …
biomolecular discovery and histopathological applications. Conventional MSI technologies …
Map** enzyme activity in living systems by real-time mid-infrared photothermal imaging of nitrile chameleons
Simultaneous spatial map** of the activity of multiple enzymes in a living system can
elucidate their functions in health and disease. However, methods based on monitoring …
elucidate their functions in health and disease. However, methods based on monitoring …
High-resolution imaging and identification of biomolecules using Nano-DESI coupled to ion mobility spectrometry
Simultaneous spatial localization and structural characterization of molecules in complex
biological samples currently represents an analytical challenge for mass spectrometry …
biological samples currently represents an analytical challenge for mass spectrometry …
Venom systems as models for studying the origin and regulation of evolutionary novelties
A central goal in biology is to determine the ways in which evolution repeats itself. One of the
most remarkable examples in nature of convergent evolutionary novelty is animal venom …
most remarkable examples in nature of convergent evolutionary novelty is animal venom …
Multi‐level convergence of complex traits and the evolution of bioluminescence
Evolutionary convergence provides natural opportunities to investigate how, when, and why
novel traits evolve. Many convergent traits are complex, highlighting the importance of …
novel traits evolve. Many convergent traits are complex, highlighting the importance of …
Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …
as toxins, have been fine-tuned over millions of years into highly effective biochemical …
Spatial analysis of the osteoarthritis microenvironment: techniques, insights, and applications
Osteoarthritis (OA) is a debilitating degenerative disease affecting multiple joint tissues,
including cartilage, bone, synovium, and adipose tissues. OA presents diverse clinical …
including cartilage, bone, synovium, and adipose tissues. OA presents diverse clinical …
Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome
Fatty acid isomers are responsible for an under-reported lipidome diversity across all
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …