Lipids, as one of the three primary energy sources, provide energy for all cellular life
activities. Lipids are also known to be involved in the formation of cell membranes and play …

The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype …

The vast majority of breast cancer death is a result of metastasis. Thus, accurate
identification of patients who are likely to have metastasis is expected to improve survival …

MYC is one of the most studied oncogenes that is known to promote cell proliferation. We
utilized MYC targets v1 and MYC targets v2 scores of gene set variation analysis and …

E2F transcription factors play critical roles in the cell cycle. Therefore, their activity is
expected to reflect tumor aggressiveness and responsiveness to therapy. We scored 3905 …

Background ABC transporters have attracted considerable attention for their function as drug
transporters in a broad range of tumours and are therefore considered as major players in …

Angiogenesis is one of the hallmarks of cancer. We hypothesized that intra-tumoral
angiogenesis correlates with inflammation and metastasis in breast cancer patients. To test …

Breast cancer is the most common malignant tumor in females worldwide. Chemotherapy is
the standard breast cancer treatment; however, chemoresistance is often seen in patients …

Many inflammatory mediators are involved in the process of carcinogenesis and cancer
progression. In addition to cytokines and chemokines, lipid mediators have recently attracted …

Chemotherapeutics are the mainstay treatment for metastatic breast cancers. However, the
chemotherapeutic failure caused by multidrug resistance (MDR) remains a pivotal obstacle …