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Interferons and proinflammatory cytokines in pregnancy and fetal development
Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …
[HTML][HTML] Stress and the HPA axis: balancing homeostasis and fertility
An organism's reproductive fitness is sensitive to the environment, integrating cues of
resource availability, ecological factors, and hazards within its habitat. Events that challenge …
resource availability, ecological factors, and hazards within its habitat. Events that challenge …
Prevalence and clinical significance of sterile intra‐amniotic inflammation in patients with preterm labor and intact membranes
Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …
Sterile inflammation and pregnancy complications: a review
Inflammation is essential for successful embryo implantation, pregnancy maintenance and
delivery. In the last decade, important advances have been made in regard to endogenous …
delivery. In the last decade, important advances have been made in regard to endogenous …
[HTML][HTML] Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National …
Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …
Spontaneous preterm birth: Involvement of multiple feto-maternal tissues and organ systems, differing mechanisms, and pathways
Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …
programming of various tissues and organ systems contributing to adult-onset diseases at a …
Psychosocial stress in pregnancy and preterm birth: associations and mechanisms
Aims: Psychosocial stress during pregnancy (PSP) is a risk factor of growing interest in the
etiology of preterm birth (PTB). This literature review assesses the published evidence …
etiology of preterm birth (PTB). This literature review assesses the published evidence …
Interleukin-6 in pregnancy and gestational disorders
IL6 is a multifunctional cytokine with pivotal roles in the inflammatory response and in
directing T cell differentiation in adaptive immunity. IL6 is widely expressed in the female …
directing T cell differentiation in adaptive immunity. IL6 is widely expressed in the female …
[HTML][HTML] Progesterone: a unique hormone with immunomodulatory roles in pregnancy
Progesterone is well known for its numerous endocrinologic roles in pregnancy but is also
endowed with fascinating immunomodulatory capabilities. It can downregulate the induction …
endowed with fascinating immunomodulatory capabilities. It can downregulate the induction …
Pig blastocyst–uterine interactions
The litter-bearing pig is an invaluable model for research in reproductive biology. Spherical
pig blastocysts on Day 10 of pregnancy undergo rapid morphological changes to tubular …
pig blastocysts on Day 10 of pregnancy undergo rapid morphological changes to tubular …