Background: Plant derived products are not only served as dietary components but also
used to treat and prevent the inflammatory associated diseases like cancer. Among the …

Simple Summary An injury to the liver caused by a drug or its metabolites is referred to as
drug-induced liver injury (DILI). The clinical manifestations of DILI are varied, and it may …

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one-third of the
global population. Understanding the metabolic pathways involved can provide insights into …

BRISC (BRCC3 isopeptidase complex) is a deubiquitinating enzyme that has been linked
with inflammatory processes, but its role in liver diseases and the underlying mechanism are …

Herbal and dietary supplements (HDS)-induced liver injury has been a great concern all
over the world. Polygonum multiflorum Thunb., a well-known Chinese herbal medicine, is …

Alcoholic liver disease (ALD), as one of the most common diseases, has become a global
threat to human health. The aim of this study was designed to investigate the …

Acetaminophen (APAP) hepatotoxicity remains the leading cause of drug-induced liver
injury due to the lack of safe and effective therapeutic agents. Berberine (BBR) is a natural …

Acute liver injury (ALI) is a severe liver disease that is characterized by sudden and massive
hepatocyte necrosis and deterioration of liver functions. Oxidative stress is increasingly …

Frequent overdose of acetaminophen (APAP) is one of the most common and important
incentives of acute hepatotoxicity. Prior to this work, our research group confirmed that black …

Background Frequent overdose of paracetamol (APAP) has become the major cause of
acute liver injury. The present study was designed to evaluate the potential protective effects …