Intervertebral disc (IVD) degeneration is a common finding on spine imaging that increases
in prevalence with age. IVD degeneration is a frequent cause of low back pain, which is a …

Key Clinical Points Nonspecific Low Back Pain Nonspecific low back pain is diagnosed on
the basis of the exclusion of specific causes, usually by means of history taking and physical …

Background Low back pain is highly prevalent and the main cause of years lived with
disability (YLDs). We present the most up-to-date global, regional, and national data on …

Low back pain (LBP) remains a musculoskeletal condition with an adverse societal impact.
Globally, LBP is highly prevalent and a leading cause of disability. This is an update to the …

Low back pain (LBP) is a major musculoskeletal disorder and the socioeconomic problem
with a high prevalence that mainly involves intervertebral disc (IVD) degeneration …

Background Opioid analgesics are commonly used for acute low back pain and neck pain,
but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a …

Background Low back pain is the leading cause of years lived with disability globally, but
most interventions have only short-lasting, small to moderate effects. Cognitive functional …

Background Low back pain (LBP) is a common musculoskeletal problem globally. Updating
the prevalence and burden of LBP is important for researchers and policy makers. This …

Importance Chronic back pain (CBP) is a leading cause of disability, and treatment is often
ineffective. Approximately 85% of cases are primary CBP, for which peripheral etiology …

Low back pain (LBP), as a leading cause of disability, is a common musculoskeletal disorder
that results in major social and economic burdens. Recent research has identified …