The advanced, metastatic differentiated thyroid cancers (DTCs) have a poor prognosis
mainly owing to radioactive iodine (RAI) refractoriness caused by decreased expression of …

The management of radioiodine refractory thyroid cancers (RAIR TC) is challenging for the
clinician. Tyrosine kinase inhibitors classically prescribed in this setting can fail due to …

The molecular mechanisms underlying the development of thyroid cancer (TC) have been
examined through extensive experiments. A large number of studies have shown that the …

Emerging evidence suggest that transcription factors play multiple roles in the development
of pancreatitis, a necroinflammatory condition lacking specific therapy. Estrogen-related …

Differentiated thyroid cancer and breast cancer account for a significant portion of endocrine-
related malignancies and predominately affect women. As hormonally responsive tissues …

Restoring sodium iodide symporter (NIS) expression and function remains a major
challenge for radioiodine therapy in anaplastic thyroid cancer (ATC). For more efficient …

Recent advances have brought forth the complex interplay between tumor cell plasticity and
its consequential impact on drug resistance and tumor recurrence, both of which are critical …

Simple Summary The composite network of stromal, immune, vascular and cancer cells,
which constitutes the tumor microenvironment (TME), has emerged as a player in thyroid …

Pancreatic ductal adenocarcinoma is one of the most aggressive solid tumours of the
pancreas, characterised by a five-year survival rate less than 8%. Recent reports that …

Molecular imaging based personalized therapy has been a fascinating concept for
individualized therapeutic strategy, which is able to attain the highest efficacy and reduce …