[HTML][HTML] MALAT1 Long Non-Coding RNA: Functional Implications

G Arun, D Aggarwal, DL Spector - Non-coding RNA, 2020 - mdpi.com
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H **, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

The roles of long noncoding RNAs in breast cancer metastasis

L Liu, Y Zhang, J Lu - Cell Death & Disease, 2020 - nature.com
Breast cancer is the most significant threat to female health. Breast cancer metastasis is the
major cause of mortality in breast cancer patients. To fully unravel the molecular …

[HTML][HTML] Gene regulation by antisense transcription: A focus on neurological and cancer diseases

S Najafi, SC Tan, P Raee, Y Rahmati… - Biomedicine & …, 2022 - Elsevier
Advances in high-throughput sequencing over the past decades have led to the
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …

Expression and Prognostic Characteristics of m6 A RNA Methylation Regulators in Breast Cancer

B Zhang, Y Gu, G Jiang - Frontiers in Genetics, 2020 - frontiersin.org
Purpose N6-methyladenosine (m6A) is the most prevalent modification in mRNA
methylation which has a wide effect on biological functions. This study aims to figure out the …

Multiple function of lncRNA MALAT1 in cancer occurrence and progression

F Malakoti, N Targhazeh, H Karimzadeh… - Chemical biology & …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …

The crosstalk between lncRNAs and the Hippo signalling pathway in cancer progression

C Tu, K Yang, L Wan, J He, L Qi, W Wang… - Cell …, 2020 - Wiley Online Library
LncRNAs play a pivotal role in the regulation of epigenetic modification, cell cycle,
differentiation, proliferation, migration and other physiological activities. In particular …

[HTML][HTML] Long non-coding RNAs and their “discrete” contribution to IBD and Johne's disease—What stands out in the current picture? A comprehensive review

KA Triantaphyllopoulos - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNA) have paved the way to new perspectives on the regulation of
gene expression, not only in biology and medicine, but also in associated fields and …

Long noncoding RNAs in ubiquitination, protein degradation, and human diseases

P Guha, A Chini, A Rishi, SS Mandal - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Protein stability and turnover is critical in normal cellular and physiological process and their
misregulation may contribute to accumulation of unwanted proteins causing cellular …

Role of MALAT1 in gynecological cancers: Pathologic and therapeutic aspects

FH Qiao, M Tu, HY Liu - Oncology Letters, 2021 - spandidos-publications.com
Gynecological cancers, including breast, ovarian, uterine, vaginal, cervical and vulvar
cancers are among the major threats to modern life, particularly to female health. Long non …