Obesity as a Condition determined by Food Addiction: should Brain Endocannabinoid System alterations be the cause and its Modulation the Solution?
Obesity is a complex disorder, and the number of people affected is growing every day. In
recent years, research has confirmed the hypothesis that food addiction is a determining …
recent years, research has confirmed the hypothesis that food addiction is a determining …
Potential of fatty acid amide hydrolase (FAAH), monoacylglycerol lipase (MAGL), and diacylglycerol lipase (DAGL) enzymes as targets for obesity treatment: a …
The endocannabinoid system (ECS) plays an integral role in maintaining metabolic
homeostasis and may affect hunger, caloric intake, and nutrient absorption. Obesity has …
homeostasis and may affect hunger, caloric intake, and nutrient absorption. Obesity has …
PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells
Immunolabeling and autoradiography have traditionally been applied as the methods-of-
choice to visualize and collect molecular information about physiological and pathological …
choice to visualize and collect molecular information about physiological and pathological …
Neurogenetic and epigenetic aspects of cannabinoids
Cannabis is one of the most commonly used and abused illicit drugs in the world today. The
United States (US) currently has the highest annual prevalence rate of cannabis …
United States (US) currently has the highest annual prevalence rate of cannabis …
Elevated brain fatty acid amide hydrolase induces depressive-like phenotypes in rodent models: a review
D Rafiei, NJ Kolla - International Journal of Molecular Sciences, 2021 - mdpi.com
Altered activity of fatty acid amide hydrolase (FAAH), an enzyme of the endocannabinoid
system, has been implicated in several neuropsychiatric disorders, including major …
system, has been implicated in several neuropsychiatric disorders, including major …
Fatty acid amide hydrolase: An integrative clinical perspective
AD Santoso, D De Ridder - Cannabis and Cannabinoid Research, 2023 - liebertpub.com
Introduction: Fatty acid amide hydrolase (FAAH) is one of the main terminating enzymes of
the endocannabinoid system (ECS). Since being discovered in 1996, the modulation of …
the endocannabinoid system (ECS). Since being discovered in 1996, the modulation of …
Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3
MG Nashed, S Waye, SMN Hasan, D Nguyen… - …, 2022 - Springer
Rationale The voltage-insensitive, small-conductance calcium-activated potassium (SK)
channel is a key regulator of neuronal depolarization and is implicated in the …
channel is a key regulator of neuronal depolarization and is implicated in the …
Peripheral endocannabinoids in major depressive disorder and alcohol use disorder: a systematic review
JJ Fuentes, J Mayans, M Guarro, I Canosa… - BMC psychiatry, 2024 - Springer
Abstract Background Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD)
are two high-prevalent conditions where the Endocannabinoid system (ECS) is believed to …
are two high-prevalent conditions where the Endocannabinoid system (ECS) is believed to …
High genes: Genetic underpinnings of cannabis use phenotypes
Cannabis is one of the most widely used substances across the globe and its use has a
substantial heritable component. However, the heritability of cannabis use varies according …
substantial heritable component. However, the heritability of cannabis use varies according …
[HTML][HTML] The contributions of the endocannabinoid system and stress on the neural processing of reward stimuli
The brain endocannabinoid system plays a crucial role in reward processes by mediating
appetitive learning and encoding the reinforcing properties of substances. Evidence also …
appetitive learning and encoding the reinforcing properties of substances. Evidence also …