Nanoemulsion: an emerging novel technology for improving the bioavailability of drugs

Preeti, S Sambhakar, R Malik, S Bhatia… - …, 2023 - Wiley Online Library
The pharmaceutical sector has made considerable strides recently, emphasizing improving
drug delivery methods to increase the bioavailability of various drugs. When used as a …

Nanoemulgel as an approach to improve the biopharmaceutical performance of lipophilic drugs: Contemporary research and application

MZ Ahmad, J Ahmad, MY Alasmary, S Akhter… - Journal of Drug Delivery …, 2022 - Elsevier
Abstract The vast majority (≥ 40%) of new drugs developed in drug discovery research or
high-throughput screening are poorly aqueous soluble and lipophilic in nature. This …

Preparation and characterization of curcumin nanoemulgel utilizing ultrasonication technique for wound healing: In vitro, ex vivo, and in vivo evaluation

MS Algahtani, MZ Ahmad, IH Nourein, HA Albarqi… - Gels, 2021 - mdpi.com
Hydrogels being a drug delivery system has great significance particularly for topical
application in cutaneous open wound. Its specific physicochemical properties such as non …

Nanostructured lipid carrier–mediated transdermal delivery of aceclofenac hydrogel present an effective therapeutic approach for inflammatory diseases

NK Garg, N Tandel, SK Bhadada… - Frontiers in …, 2021 - frontiersin.org
Aceclofenac (ACE), a cyclooxygenase-2 inhibitor, is the derivative of the diclofenac group
that has been in use for the symptomatic treatment of systemic inflammatory autoimmune …

Thymoquinone loaded topical nanoemulgel for wound healing: formulation design and in-vivo evaluation

MS Algahtani, MZ Ahmad, IA Shaikh, BA Abdel-Wahab… - Molecules, 2021 - mdpi.com
Thymoquinone is a natural bioactive with significant therapeutic activity against multiple
ailments including wound healing. The poor aqueous solubility and low skin permeability …

Xanthan and gum acacia modified olive oil based nanoemulsion as a controlled delivery vehicle for topical formulations

K Kobra, SY Wong, MAJ Mazumder, X Li… - International Journal of …, 2023 - Elsevier
In this study, olive oil nanoemulsion modified with xanthan gum and gum acacia was
explored as a potential controlled topical delivery vehicle. Oil-in-water nanoemulsion …

Development of a curcumin-loaded lecithin/chitosan nanoparticle utilizing a box-behnken design of experiment: formulation design and influence of process …

IA Walbi, MZ Ahmad, J Ahmad, MS Algahtani, AS Alali… - Polymers, 2022 - mdpi.com
Curcumin (CUR) has impressive pharmacologic properties, including cardioprotective,
neuroprotective, antimicrobial, and anticancer activity. However, the pharmaceutical …

Enhanced in vivo wound healing efficacy of a novel piperine-containing bioactive hydrogel in excision wound rat model

SA Alsareii, J Ahmad, A Umar, MZ Ahmad, IA Shaikh - Molecules, 2023 - mdpi.com
These days an extensive amount of the attention of researchers is focused towards
exploring bioactive compounds of natural or herbal origin for therapeutic intervention in …

Development of nanogel loaded with lidocaine for wound-healing: Illustration of improved drug deposition and skin safety analysis

A Ali, A Ali, MA Rahman, MH Warsi, M Yusuf, P Alam - Gels, 2022 - mdpi.com
A wound refers to a cut or blow that may result in primary or secondary infection or even
death, if untreated. In the current study, we have explored the wound-healing properties of …

An overview of nanoemulgels for bioavailability enhancement in inflammatory conditions via topical delivery

DK Lal, B Kumar, AS Saeedan, MN Ansari - Pharmaceutics, 2023 - mdpi.com
The anti-inflammatory drugs that are generally available possess the disadvantage of
hydrophobicity, which leads to poor permeability and erratic bioavailability. Nanoemulgels …