Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications

JP Delling, TM Boeckers - Journal of Neurodevelopmental Disorders, 2021 - Springer
Background Autism spectrum disorder (ASD) is a neurodevelopmental condition, which is
characterized by clinical heterogeneity and high heritability. Core symptoms of ASD include …

Autism spectrum disorder and pupillometry: A systematic review and meta-analysis

L de Vries, I Fouquaet, B Boets, G Naulaers… - Neuroscience & …, 2021 - Elsevier
Pupillometry, measuring pupil size and reactivity, has been proposed as a measure of
autonomic nervous system functioning, the latter which might be altered in individuals with …

[HTML][HTML] PupilEXT: Flexible open-source platform for high-resolution pupillometry in vision research

B Zandi, M Lode - Frontiers in neuroscience, 2021 - frontiersin.org
The human pupil behavior has gained increased attention due to the discovery of the
intrinsically photosensitive retinal ganglion cells and the afferent pupil control path's role as …

Differences in the pupillary responses to evening light between children and adolescents

LE Hartstein, MK LeBourgeois, MT Durniak… - Journal of Physiological …, 2024 - Springer
Background In the mammalian retina, intrinsically-photosensitive retinal ganglion cells
(ipRGC) detect light and integrate signals from rods and cones to drive multiple non-visual …

Investigating the development of the autonomic nervous system in infancy through pupillometry

LM de Vries, S Amelynck, P Nyström… - Journal of Neural …, 2023 - Springer
We aim to investigate early developmental trajectories of the autonomic nervous system
(ANS) as indexed by the pupillary light reflex (PLR) in infants with (ie preterm birth, feeding …

Development of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3‐year ASD diagnosis

LA Fish, P Nyström, T Gliga, A Gui… - Journal of Child …, 2021 - Wiley Online Library
Background Although autism spectrum disorder (ASD) is heritable, the mechanisms through
which genes contribute to symptom emergence remain unclear. Investigating candidate …

Gaze following and pupil dilation as early diagnostic markers of autism in toddlers

R Camero, V Martínez, C Gallego - Children, 2021 - mdpi.com
Background: Children with autism spectrum disorder (ASD) show certain characteristics in
visual attention. These may generate differences with non-autistic children in the integration …

Pupil size and pupillary light reflex in early infancy: heritability and link to genetic liability to schizophrenia

AM Portugal, MJ Taylor, C Viktorsson… - Journal of Child …, 2022 - Wiley Online Library
Background Measures based on pupillometry, such as the pupillary light reflex (PLR) and
baseline pupil size, reflect physiological responses linked to specific neural circuits that …

Eye-Tracking Biomarkers and Autism Diagnosis in Primary Care

B Keehn, P Monahan, B Enneking, T Ryan… - JAMA Network …, 2024 - jamanetwork.com
Importance Finding effective and scalable solutions to address diagnostic delays and
disparities in autism is a public health imperative. Approaches that integrate eye-tracking …

Increasing Vegetable Diversity Consumption impacts the sympathetic nervous system activity in school-aged children

F de Castro Mendes, I Paciência, JC Rufo, M Farraia… - Nutrients, 2021 - mdpi.com
Evidence about the impact of vegetable and fruit diversity consumption on the autonomic
nervous system (ANS) functioning is scarce. In this cross-sectional study (513 participants …