Molecular basis of human sperm capacitation

LC Puga Molina, GM Luque, PA Balestrini… - Frontiers in cell and …, 2018 - frontiersin.org
In the early 1950s, Austin and Chang independently described the changes that are
required for the sperm to fertilize oocytes in vivo. These changes were originally grouped …

Mysteries and unsolved problems of mammalian fertilization and related topics

R Yanagimachi - Biology of reproduction, 2022 - academic.oup.com
Mammalian fertilization is a fascinating process that leads to the formation of a new
individual. Eggs and sperm are complex cells that must meet at the appropriate time and …

Fertilization: a sperm's journey to and interaction with the oocyte

M Ikawa, N Inoue, AM Benham… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Mammalian fertilization comprises sperm migration through the female reproductive tract,
biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct …

Sperm migration, selection, survival, and fertilizing ability in the mammalian oviduct

C Mahé, AM Zlotkowska, K Reynaud… - Biology of …, 2021 - academic.oup.com
In vitro fertilization (IVF) gives rise to embryos in a number of mammalian species and is
currently widely used for assisted reproduction in humans and for genetic purposes in cattle …

Spermatozoa as functional components of robotic microswimmers

V Magdanz, M Medina‐Sánchez, L Schwarz… - Advanced …, 2017 - Wiley Online Library
In recent years, the combination of synthetic micro‐and nanomaterials with spermatozoa as
functional components has led to the development of tubular and helical spermbots …

[HTML][HTML] CatSper: The complex main gate of calcium entry in mammalian spermatozoa

R Rahban, S Nef - Molecular and cellular endocrinology, 2020 - Elsevier
Abstract Calcium ions (Ca 2+) are involved in nearly every aspect of cellular life. They are
one of the most abundant elements in mammals and play a vital role in physiological and …

[HTML][HTML] Mouse sperm begin to undergo acrosomal exocytosis in the upper isthmus of the oviduct

FA La Spina, LCP Molina, A Romarowski… - Developmental …, 2016 - Elsevier
Recent evidence demonstrated that most fertilizing mouse sperm undergo acrosomal
exocytosis (AE) before binding to the zona pellucida of the eggs. However, the sites where …

Molecular mechanism for human sperm chemotaxis mediated by progesterone

ME Teves, HA Guidobaldi, DR Unates, R Sanchez… - PloS one, 2009 - journals.plos.org
Sperm chemotaxis is a chemical guiding mechanism that may orient spermatozoa to the egg
surface. A picomolar concentration gradient of Progesterone (P), the main steroidal …

Human sperm steer with second harmonics of the flagellar beat

G Saggiorato, L Alvarez, JF Jikeli, UB Kaupp… - Nature …, 2017 - nature.com
Sperm are propelled by bending waves traveling along their flagellum. For steering in
gradients of sensory cues, sperm adjust the flagellar waveform. Symmetric and asymmetric …

Sperm chemotaxis and regulation of flagellar movement by Ca2+

M Yoshida, K Yoshida - MHR: Basic science of reproductive …, 2011 - academic.oup.com
The chemotaxis of sperm towards eggs is a widespread phenomenon that occurs in most
forms of life from lower plants to mammals and plays important roles in ensuring fertilization …