Pyridine-based ring structures are widely employed in drug design due to their significant
impact on pharmacological activity, resulting in the development of various broad-spectrum …

Breast cancer is the most common cancer among women. Currently, it poses a significant
threat to the healthcare system due to the emerging resistance and toxicity of available drug …

Herein, we synthesized some new imidazole-moprholine-1, 2, 4-oxadiazoles (7a-7o) and
characterized their structures using 1 H NMR, 13 C NMR, ESI-mass and CHN analyses …

New 4‐nitrobenzyl derivatives were designed and synthesised by nucleophilic substitution
reactions of 4‐nitrobenzyl bromide with malonic acid and its derivatives. The synthesised …

A prominent heterocyclic system found in medications and natural goods is indoles. Due to
the significance of this important ring system, a fresh batch of unique indole derivatives was …

A novel Schiff base ligand (L), bearing N2O2 donor sites, was derived from the
condensation of 5-chloromethylisophthaldehyde and phenylpropanolamine (PPA) …

Indoles and their derivatives have long been studied for their anticancer properties. Breast
cancer has been treated using indole‐3‐carbinol, Indirubins, and many other naturally …

The tetra‐substituted imidazole offers more possibilities for modification and
functionalization, allowing for fine‐tuning of the compound's biological activity. The …

ABSTRACT New chalcone derivatives (7a-7j) and thiosemicarbazone derivatives (9a-9j)
containing 2-n-Butyl-4-chloro-5-formyl imidazole nucleus have been synthesized and their …

This book chapter delves into the burgeoning field of pharmacological applications of N-
heterocycles, focussing particularly on pyrazole, imidazole and triazole derivatives. N …