Inflammation and HIV transmission in sub-Saharan Africa

R Kaul, J Prodger, V Joag, B Shannon… - Current HIV/AIDS …, 2015 - Springer
While the per-contact risk of sexual HIV transmission is relatively low, it is fourfold higher in
sub-Saharan Africa, and this may partly explain the major global disparities that exist in HIV …

Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system

D van Baarle, A Tsegaye, F Miedema, A Akbar - Immunology letters, 2005 - Elsevier
There is a generalized age-related decline in immune responses which leads to increased
susceptibility of elderly to infection and, possibly, to autoimmune disease and cancer. This is …

Interrogating the impact of intestinal parasite-microbiome on pathogenesis of COVID-19 in sub-Saharan Africa

D Wolday, G Tasew, W Amogne, B Urban… - Frontiers in …, 2021 - frontiersin.org
Intestinal parasitic infections affect more than 2 billion people throughout the world with
disproportionately high prevalence rates in Low-and Middle-Income Countries …

Albendazole treatment of HIV-1 and helminth co-infection: a randomized, double-blind, placebo-controlled trial

JL Walson, PA Otieno, M Mbuchi, BA Richardson… - Aids, 2008 - journals.lww.com
Objective: Several co-infections have been shown to impact the progression of HIV-1
infection. We sought to determine if treatment of helminth co-infection in HIV-1-infected …

Deworming helminth co‐infected individuals for delaying HIV disease progression

JL Walson, BR Herrin… - Cochrane database of …, 2009 - cochranelibrary.com
Background The HIV‐1 pandemic has disproportionately affected individuals in resource‐
constrained settings where other infectious diseases, such as helminth infections, also are …

Intestinal parasitosis in relation to CD4+ T cells levels and anemia among HAART initiated and HAART naive pediatric HIV patients in a model ART center in Addis …

HM Mengist, B Taye, A Tsegaye - PloS one, 2015 - journals.plos.org
Background Intestinal parasites (IPs) are major concerns in most develo** countries
where HIV/AIDS cases are concentrated and almost 80% of AIDS patients die of AIDS …

HIV and helminth co‐infection: is deworming necessary?

G Borkow, Z Bentwich - Parasite immunology, 2006 - Wiley Online Library
We have previously suggested that helminth infections play a major role in the pathogenesis
of HIV‐1 infection in Africa and other develo** areas, due to their profound effects on the …

Role of CD4/CD8 ratio on the incidence of tuberculosis in HIV-infected patients on antiretroviral therapy followed up for more than a decade

D Wolday, Y Kebede, D Legesse, DS Siraj, JA McBride… - PloS one, 2020 - journals.plos.org
Background The role of CD4/CD8 ratio on the incidence of tuberculosis (TB) in patients on
antiretroviral therapy (ART) is unknown. Thus, we sought to determine whether the …

T Cell Activation in HIV-Seropositive Ugandans: Differential Associations with Viral Load, CD4+ T Cell Depletion, and Coinfection

MP Eggena, B Barugahare, M Okello… - The Journal of …, 2005 - academic.oup.com
Immune activation is thought to play a major role in the pathogenesis of human
immunodeficiency virus (HIV). This effect may be particularly relevant in Africa, where …

[HTML][HTML] Impacts of neglected tropical disease on incidence and progression of HIV/AIDS, tuberculosis, and malaria: scientific links

GG Simon - International Journal of Infectious Diseases, 2016 - Elsevier
The neglected tropical diseases (NTDs) are the most common infections of humans in Sub-
Saharan Africa. Virtually all of the population living below the World Bank poverty figure is …