Humoral innate immunity and acute-phase proteins

A Mantovani, C Garlanda - New England Journal of Medicine, 2023 - Mass Medical Soc
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Immune responses to human fungal pathogens and therapeutic prospects

MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America

TF Patterson, GR Thompson III… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Worldwide emergence of resistance to antifungal drugs challenges human health and food security

MC Fisher, NJ Hawkins, D Sanglard, SJ Gurr - Science, 2018 - science.org
The recent rate of emergence of pathogenic fungi that are resistant to the limited number of
commonly used antifungal agents is unprecedented. The azoles, for example, are used not …

Aspergillus fumigatus morphology and dynamic host interactions

FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19

E Brunetta, M Folci, B Bottazzi, M De Santis, G Gritti… - Nature …, 2021 - nature.com
Abstract Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity,
involved in resistance to selected pathogens and in the regulation of inflammation,–. The …

Breakthrough invasive fungal infections: Who is at risk?

JD Jenks, OA Cornely, SCA Chen, GR Thompson III… - Mycoses, 2020 - Wiley Online Library
The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has
changed over the last few decades, partially due to the increased use of antifungal agents to …

[HTML][HTML] PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer

E Bonavita, S Gentile, M Rubino, V Maina, R Papait… - Cell, 2015 - cell.com
PTX3 is an essential component of the humoral arm of innate immunity, playing a
nonredundant role in resistance against selected microbes and in the regulation of …

Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia.

Y Schmiedel, S Zimmerli - Swiss medical weekly, 2016 - boris.unibe.ch
Every year, Candida, Aspergillus, Cryptococcus and Pneumocystis infect an estimated two
million individuals worldwide. Most are immunocompromised or critically ill. Candida is the …

Defining breakthrough invasive fungal infection–Position paper of the mycoses study group education and research consortium and the European Confederation of …

OA Cornely, M Hoenigl, C Lass‐Flörl, SCA Chen… - Mycoses, 2019 - Wiley Online Library
Breakthrough invasive fungal infections (IFI s) have emerged as a significant problem in
patients receiving systemic antifungals; however, consensus criteria for defining …