The development of an artificial pancreas for the treatment of insulin-dependent diabetes is
a highly desired endeavor for patients, physicians, scientists, and engineers. Historical …

Background The last two decades have witnessed unprecedented technological progress in
the development of continuous glucose sensors, resulting in the first generation of …

Materials and Methods We searched MEDLINE and the Cochrane Library for RCTs,
observational studies, review articles, meta-analyses, and editorials on IIT in the …

Diabetes is a disease that is now regarded an epidemic in the world and a sign-icant e? ort
is directed towards? nding better ways to manage diabetes. Kee** bloodglucoselevelsasclosetonormalaspossi …

In this paper, the design of an expert proportional-integral-derivative (PID) control system for
blood glucose regulation in patients, such as the intensive care population, is described …

Although the symptoms of severe hyperglycemia have been known for millennia, the
laboratory measurement of blood glucose was a lengthy and labor-intensive process until …

Introduction Closed-loop (CL) systems modulate insulin delivery according to glucose levels
without nurse input. In a prospective randomized controlled trial, we evaluated the feasibility …

Introduction Critically ill patients may benefit from strict glucose control. An objective
measure of hyperglycaemia for assessing glucose control in acutely ill patients should …

Advances in diabetes technology over the past decades have revolutionized patient care
and diabetes management. The use of this technology, including continuous glucose …

Tight glycemic control (TGC) has emerged as a major research focus in critical care due to
its potential to simultaneously reduce both mortality and costs. However, repeating initial …