Bioactive Secondary Metabolites from Bacillus subtilis: A Comprehensive Review

F Kaspar, P Neubauer, M Gimpel - Journal of natural products, 2019 - ACS Publications
Bacillus subtilis is widely underappreciated for its inherent biosynthetic potential. This report
comprehensively summarizes the known bioactive secondary metabolites from B. subtilis …

Classification and Multifaceted Potential of Secondary Metabolites Produced by Bacillus subtilis Group: A Comprehensive Review

S Iqbal, F Begum, AA Rabaan, M Aljeldah… - Molecules, 2023 - mdpi.com
Despite their remarkable biosynthetic potential, Bacillus subtilis have been widely
overlooked. However, their capability to withstand harsh conditions (extreme temperature …

Cyclic dipeptides: The biological and structural landscape with special focus on the anti-cancer proline-based scaffold

J Bojarska, A Mieczkowski, ZM Ziora, M Skwarczynski… - Biomolecules, 2021 - mdpi.com
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

Identification of non-volatile and volatile organic compounds produced by Bacillus siamensis LZ88 and their antifungal activity against Alternaria alternata

D Wang, Y Li, Y Yuan, D Chu, J Cao, G Sun, Y Ai, Z Cui… - Biological Control, 2022 - Elsevier
Our previous study identified that Bacillus siamensis strain LZ88 has significant antagonistic
activity against a variety of pathogenic fungi, especially against Alternaria alternata, which …

Recent achievements and perspectives for large-scale recombinant production of antimicrobial peptides

D Wibowo, CX Zhao - Applied microbiology and biotechnology, 2019 - Springer
Antibiotic resistance poses a growing threat to global public health. It is urgent to develop
new alternative antibiotics. Antimicrobial peptide (AMP) is a diverse class of natural …

Inducing secondary metabolite production of Aspergillus sydowii through microbial co-culture with Bacillus subtilis

Y Sun, WC Liu, X Shi, HZ Zheng, ZH Zheng, XH Lu… - Microbial Cell …, 2021 - Springer
Background The co-culture strategy which mimics natural ecology by constructing an
artificial microbial community is a useful tool to activate the biosynthetic gene clusters to …

The cave microbiome as a source for drug discovery: reality or pipe dream?

S Ghosh, N Kuisiene, N Cheeptham - Biochemical pharmacology, 2017 - Elsevier
This review highlights cave habitats, cave microbiomes and their potential for drug
discovery. Such studies face many challenges, including access to remote and pristine …

Marine macrolides with antibacterial and/or antifungal activity

TM Karpiński - Marine drugs, 2019 - mdpi.com
Currently, the increasing resistance of microorganisms to antibiotics is a serious problem.
Marine organisms are the source of thousands of substances, which also have antibacterial …

Antibacterial compounds from marine bacteria, 2010–2015

C Schinke, T Martins, SCN Queiroz… - Journal of natural …, 2017 - ACS Publications
This review summarizes the reports on antibacterial compounds that have been obtained
from marine-derived bacteria during the period 2010–2015. Over 50 active compounds were …

Antifungal potential of marine natural products

EM El-Hossary, C Cheng, MM Hamed… - European journal of …, 2017 - Elsevier
Fungal diseases represent an increasing threat to human health worldwide which in some
cases might be associated with substantial morbidity and mortality. However, only few …