Taxol®(generic name paclitaxel) represents one of the most clinically valuable natural
products known to mankind in the recent past. More than two decades have elapsed since …

Although rational method and global technique have been successfully applied in strain
improvement respectively, the demand for engineering complex phenotypes required …

Background Endophytic fungi represent underexplored resource of novel lead compounds
and have a capacity to produce diverse class of plant secondary metabolites. Here we …

Within a plant, there can exist an ecosystem of pathogens and endophytes, the latter
described as bacterial and fungal inhabitants that thrive without causing disease to the host …

Taxol, a phyto-extracted diterpenoid, is the most commercially needed drug in cancer
chemotherapy. In spite of the microbial production of taxol being successful and prospective …

The use of microorganisms in industry has enabled the (over) production of various
compounds (eg, primary and secondary metabolites, proteins and enzymes) that are …

Paclitaxel is a potent and widely used antitumor agent. Considerable worldwide research
efforts have been carried out on different production alternatives. Since the description of the …

Heterokaryosis is an integral part of the parasexual cycle used by predominantly asexual
fungi to introduce and maintain genetic variation in populations. Research into fungal …

The economical and efficient commercial production of second-generation bioethanol
requires fermentation microorganisms capable of entirely and rapidly utilizing all sugars in …

An upsurge in the bioeconomy drives the need for engineering microorganisms with
increasingly complex phenotypes. Gains in productivity of industrial microbes depend on the …