Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) can provide long-term
symptom relief for treatment-resistant depression (TRD). However, achieving stable recovery …

Objective: The purpose of this article was to inform the first-line treatment choice between
cognitive-behavioral therapy (CBT) or an antidepressant medication for treatment-naive …

Social behavior encompasses a number of distinctive and complex constructs that form the
core elements of human imitative culture, mainly represented as either affiliative or …

Despite being considered primarily a mood disorder, major depressive disorder (MDD) is
characterized by cognitive and decision making deficits. Recent research has employed …

Anhedonia, or the loss of pleasure in previously rewarding stimuli, is a core symptom of
major depressive disorder that may reflect an underlying dysregulation in reward …

The medial prefrontal cortex (mPFC) is critically involved in numerous cognitive functions,
including attention, inhibitory control, habit formation, working memory and long-term …

Mood and anxiety disorders are prevalent conditions affecting one out of four people during
lifetime. The development of high validity animal models to study these disorders has been a …

The efficacy and duration of memory storage is regulated by neuromodulatory transmitter
actions. While the modulatory transmitter serotonin (5-HT) plays an important role in implicit …