Wnt signaling in orofacial clefts: crosstalk, pathogenesis and models

K Reynolds, P Kumari… - Disease models & …, 2019 - journals.biologists.com
Diverse signaling cues and attendant proteins work together during organogenesis,
including craniofacial development. Lip and palate formation starts as early as the fourth …

Neural crest and the origin of species‐specific pattern

RA Schneider - genesis, 2018 - Wiley Online Library
For well over half of the 150 years since the discovery of the neural crest, the special ability
of these cells to function as a source of species‐specific pattern has been clearly …

Craniofacial studies in chicken embryos confirm the pathogenicity of human FZD2 variants associated with Robinow syndrome

SS Tophkhane, K Fu, EM Verheyen… - Disease Models & …, 2024 - journals.biologists.com
Robinow syndrome is a rare disease caused by variants of seven WNT pathway genes.
Craniofacial features include widening of the nasal bridge and jaw hypoplasia. We used the …

Evolutionary mechanisms modulating the mammalian skull development

S Kyomen, AP Murillo-Rincón… - … Transactions of the …, 2023 - royalsocietypublishing.org
Mammals possess impressive craniofacial variation that mirrors their adaptation to diverse
ecological niches, feeding behaviour, physiology and overall lifestyle. The spectrum of …

Environmental thermal stress induces neuronal cell death and developmental malformations in reptiles

TJ Sanger, L Harding, J Kyrkos… - Integrative …, 2021 - academic.oup.com
Every stage of organismal life history is being challenged by global warming. Many species
are already experiencing temperatures approaching their physiological limits; this is …

The process of animal domestication

M Sánchez-Villagra - 2022 - torrossa.com
Domestic animals are ubiquitous. In contrast to the biodiversity crisis currently impacting
many kinds of animals and plants, not a single domesticated species is endangered …

The MID1 gene product in physiology and disease

R Baldini, M Mascaro, G Meroni - Gene, 2020 - Elsevier
MID1 is an E3 ubiquitin ligase of the Tripartite Motif (TRIM) subfamily of RING-containing
proteins, hence also known as TRIM18. MID1 is a microtubule-binding protein found in …

[HTML][HTML] Loss of normal facial asymmetry in schizophrenia and bipolar disorder: implications for development of brain asymmetry in psychotic illness

FM Sukno, BD Kelly, A Lane, S Katina, MA Rojas… - Psychiatry …, 2024 - Elsevier
Abstract Development of the craniofacies occurs in embryological intimacy with
development of the brain and both show normal left-right asymmetries. While facial …

SHH signaling pathway drives pediatric bone sarcoma progression

F Lézot, I Corre, S Morice, F Rédini, F Verrecchia - Cells, 2020 - mdpi.com
Primary bone tumors can be divided into two classes, benign and malignant. Among the
latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary …

Craniofacial malformations and their association with brain development: the importance of a multidisciplinary approach for treatment

A Ornoy - Odontology, 2020 - Springer
The craniofacial complex develops mainly in the first trimester of pregnancy, but its final
sha** and the development of the teeth extend into the second and third trimesters. It is …