Multiple effects of growth hormone in the body: is it really the hormone for growth?

J Devesa, C Almengló… - Clinical Medicine Insights …, 2016 - journals.sagepub.com
In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

[HTML][HTML] ChatGPT and the rise of generative AI: Threat to academic integrity?

DO Eke - Journal of Responsible Technology, 2023 - Elsevier
The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

Growth hormone (GH) and cardiovascular system

D Caicedo, O Díaz, P Devesa, J Devesa - International journal of …, 2018 - mdpi.com
This review describes the positive effects of growth hormone (GH) on the cardiovascular
system. We analyze why the vascular endothelium is a real internal secretion gland, whose …

JNK signaling and its impact on neural cell maturation and differentiation

RD Castro-Torres, J Olloquequi, A Parcerisas, J Ureña… - Life Sciences, 2024 - Elsevier
Abstract C-Jun-N-terminal-kinases (JNKs), members of the mitogen-activated-protein-kinase
family, are significantly linked with neurological and neurodegenerative pathologies and …

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases

S Harguindey, D Stanciu, J Devesa, K Alfarouk… - Seminars in Cancer …, 2017 - Elsevier
During the last few years, the understanding of the dysregulated hydrogen ion dynamics and
reversed proton gradient of cancer cells has resulted in a new and integral pH-centric …

Mice lacking BCAS1, a novel myelin‐associated protein, display hypomyelination, schizophrenia‐like abnormal behaviors, and upregulation of inflammatory genes in …

T Ishimoto, K Ninomiya, R Inoue, M Koike, Y Uchiyama… - Glia, 2017 - Wiley Online Library
The abnormal expression and function of myelin‐related proteins contribute to nervous
system dysfunction associated with neuropsychiatric disorders; however, the underlying …

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Z Chaker, S Aïd, H Berry, M Holzenberger - Aging cell, 2015 - Wiley Online Library
Downregulation of insulin‐like growth factor (IGF) pathways prolongs lifespan in various
species, including mammals. Still, the cellular mechanisms by which IGF signaling controls …

Growth hormone (GH) and gonadotropin-releasing hormone (GnRH) in the central nervous system: A potential neurological combinatory therapy?

CG Martínez-Moreno, D Calderón-Vallejo… - International Journal of …, 2018 - mdpi.com
This brief review of the neurological effects of growth hormone (GH) and gonadotropin-
releasing hormone (GnRH) in the brain, particularly in the cerebral cortex, hypothalamus …