Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate
is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is …

One-carbon metabolism is a central metabolic pathway critical for the biosynthesis of several
amino acids, methyl group donors, and nucleotides. The pathway mostly relies on the …

Mantle cell lymphoma (MCL) is a subtype of mature B-cell non-Hodgkin lymphoma
characterized by a poor prognosis. First, we analyzed a series of 123 cases (GSE93291). An …

Background Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer and one of the major causes of cancer-related death. Thymidylate synthase (TYMS) …

Background Infantile hemangioma (IH) is characterized by proliferation and regression.
Methods Based on the GSE127487 dataset, the differentially expressed genes (DEGs) …

Background: The expression of thymidylate synthase (TYMS) is significantly up-regulated in
various cancers and associated with the poor prognosis of patients. However, the role of …

Thymidylate synthase (TYMS) is the crucial enzymatic precursor for DNA biosynthesis and,
therefore, the critical target for numerous types of chemotherapy, including the most …

Background: Cervical cancer (CC) is the second most common type of malignant tumor
survival rate is low in advanced stage, metastatic, and recurrent CC patients. This study …

Background Pancreatic cancer (PC) is one of the worst prognoses amongst all malignant
diseases. It is therefore of great significance to identify biomarkers with predictive clinical …

Purpose: Despite the significant association of molecular subtypes with poor prognosis in
patients with pancreatic ductal adenocarcinoma (PDAC), few efforts have been made to …