microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
Global signatures of protein and mRNA expression levels
Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …
relationship between protein and mRNA expression levels informs about the combined …
[HTML][HTML] The role of microRNAs in human diseases
AM Ardekani, MM Naeini - Avicenna journal of medical …, 2010 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in
translational repression and gene silencing and are found in all eukaryotic cells …
translational repression and gene silencing and are found in all eukaryotic cells …
Mesenchymal stem cell (MSC)-derived exosomes as novel vehicles for delivery of miRNAs in cancer therapy
B Sohrabi, B Dayeri, E Zahedi, S Khoshbakht… - Cancer Gene …, 2022 - nature.com
Mesenchymal stem cells (MSCs) are known as promising sources for cancer therapy and
can be utilized as vehicles in cancer gene therapy. MSC-derived exosomes are central …
can be utilized as vehicles in cancer gene therapy. MSC-derived exosomes are central …
[HTML][HTML] MicroRNAs: exploring new horizons in osteoarthritis
M Nugent - Osteoarthritis and cartilage, 2016 - Elsevier
Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …
morbidity. The underlying disease process is multifactorial however there is increasing focus …
[HTML][HTML] Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study
Introduction There are currently no highly sensitive and specific minimally invasive
biomarkers for detection of early-stage breast cancer. MicroRNAs (miRNAs) are present in …
biomarkers for detection of early-stage breast cancer. MicroRNAs (miRNAs) are present in …
Inorganic nanoparticle-based advanced cancer therapies: Promising combination strategies
Inorganic nanoparticles for drug delivery in cancer treatment offer many potential
advantages because they can maximize therapeutic effect through targeting ligands while …
advantages because they can maximize therapeutic effect through targeting ligands while …
[HTML][HTML] Epigenetic regulation of autophagy in gastrointestinal cancers
The development of novel therapeutic approaches is necessary to manage gastrointestinal
cancers (GICs). Considering the effective molecular mechanisms involved in tumor growth …
cancers (GICs). Considering the effective molecular mechanisms involved in tumor growth …
Exosomes: a new horizon in lung cancer
I Vanni, A Alama, F Grossi, MG Dal Bello, S Coco - Drug discovery today, 2017 - Elsevier
Highlights•Exosomes play a key part in tumorigenesis and progression of cancer.•Exosomes
can be isolated from cell culture media and almost all body fluids.•Exosomes are cargos of …
can be isolated from cell culture media and almost all body fluids.•Exosomes are cargos of …
Primary biliary cirrhosis is associated with altered hepatic microRNA expression
MicroRNAs (miRNAs) are small RNA molecules that negatively regulate protein coding
gene expression and are thought to play a critical role in many biological processes …
gene expression and are thought to play a critical role in many biological processes …