Hydrogel-based immunoregulation of macrophages for tissue repair and regeneration

R Nie, QY Zhang, ZY Feng, K Huang, CY Zou… - International Journal of …, 2024 - Elsevier
The rational design of hydrogel materials to modulate the immune microenvironment has
emerged as a pivotal approach in expediting tissue repair and regeneration. Within the …

The role of extracellular matrix (ECM) adhesion motifs in functionalised hydrogels

AJ Morwood, IA El-Karim, SA Clarke, FT Lundy - Molecules, 2023 - mdpi.com
To create functional tissue engineering scaffolds, biomaterials should mimic the native
extracellular matrix of the tissue to be regenerated. Simultaneously, the survival and …

Preparation of recombinant human collagen III protein hydrogels with sustained release of extracellular vesicles for skin wound healing

L Xu, Y Liu, L Tang, H **ao, Z Yang… - International Journal of …, 2022 - mdpi.com
Existing treatment methods encounter difficulties in effectively promoting skin wound
healing, making this a serious challenge for clinical treatment. Extracellular vesicles (EVs) …

Effects of bone surface topography and chemistry on macrophage polarization

B Özcolak, B Erenay, S Odabaş, KD Jandt… - Scientific reports, 2024 - nature.com
Surface structure plays a crucial role in determining cell behavior on biomaterials,
influencing cell adhesion, proliferation, differentiation, as well as immune cells and …

Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties

AR Namjoo, FN Abrbekoh, S Saghati, H Amini… - Stem Cell Research & …, 2023 - Springer
Muscular diseases and injuries are challenging issues in human medicine, resulting in
physical disability. The advent of tissue engineering approaches has paved the way for the …

Design of recombinant spider silk proteins for cell type specific binding

VT Trossmann, T Scheibel - Advanced Healthcare Materials, 2023 - Wiley Online Library
Cytophilic (cell‐adhesive) materials are very important for tissue engineering and
regenerative medicine. However, for engineering hierarchically organized tissue structures …

Engineering antigen-presenting cells for immunotherapy of autoimmunity

CT Smith, Z Wang, JS Lewis - Advanced Drug Delivery Reviews, 2024 - Elsevier
Autoimmune diseases are burdensome conditions that affect a significant fraction of the
global population. The hallmark of autoimmune disease is a host's immune system being …

[HTML][HTML] Laminin-derived peptide, IKVAV, modulates macrophage phenotype through integrin mediation

A Jha, E Moore - Matrix Biology Plus, 2024 - Elsevier
Macrophages are highly plastic immune cells known to exist on a spectrum of phenotypes
including pro-inflammatory (M1) or pro-healing (M2). Macrophages interact with extracellular …

Treatment of chronic osteomyelitis with gradient release of DGEA and vancomycin hydrogel-microsphere system and its mechanism

Y Zheng, Y Wang, F Sheng, S Wang, Y Zhou… - Frontiers in …, 2024 - frontiersin.org
In recent years, the treatment of chronic osteomyelitis mediated by biodegradable polymer
platforms has received increasing attention. This paper reports an advanced drug delivery …

Deciphering the Wound-Healing Potential of Collagen Peptides and the Molecular Mechanisms: A Review

Y Li, Y Lu, Y Zhao, N Zhang, Y Zhang… - Journal of Agricultural …, 2024 - ACS Publications
Collagen peptides have been reported to display various bioactivities and high
bioavailability. Recently, increasing evidence has revealed the excellent wound-healing …