Genetics of antidepressant response and treatment-resistant depression

AN Chung, TT Chen, YF Lin - Progress in Brain Research, 2023 - Elsevier
Antidepressant response, the effectiveness of antidepressants in relieving symptoms of
depression, is a complex trait influenced by both genetic and environmental factors …

The pharmacogenomics of selective serotonin reuptake inhibitors

LM García-Marín, JA Rabinowitz, Z Ceja… - …, 2022 - Taylor & Francis
Antidepressant medications are frequently used as the first line of treatment for depression.
However, their effectiveness is highly variable and influenced by genetic factors. Recently …

[HTML][HTML] Serotonin syndrome

LV Simon, TJ Torrico, M Keenaghan - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Serotonin Syndrome - StatPearls - NCBI Bookshelf US flag An official website of the United
States government Here's how you know NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Molecular mechanisms associated with antidepressant treatment on Major Depression

L Ramos-da-Silva, PT Carlson, LC Silva-Costa… - Complex …, 2021 - karger.com
Major depressive disorder (MDD) is a complex and multifactorial psychiatric disorder that
causes serious health, social, and economic concerns worldwide. The main treatment of the …

[HTML][HTML] Reveal the potent antidepressant effects of Zhi-Zi-Hou-Pu Decoction based on integrated network pharmacology and DDI analysis by deep learning

Z Zhang, X Li, Z Huang, Z Pan, L Li, Y Wang, S Wu… - Heliyon, 2024 - cell.com
Background and objective The multi-targets and multi-components of Traditional Chinese
medicine (TCM) coincide with the complex pathogenesis of depression. Zhi-Zi-Hou-Pu …

Genetic determinants of antidepressant and antipsychotic drug response

HH Stassen, S Bachmann, R Bridler… - European Archives of …, 2024 - Springer
Today, more than 90% of inpatients hospitalized with Major Depression or Schizophrenia
are treated with psychotropic drugs. Since none of the treatment options is causal, response …

Links among genetic variants and hierarchical brain structural and functional networks for antidepressant treatment: A multivariate study

Y Sun, Y Hou, X Wang, H Wang, R Yan, L Xue, Z Yao… - Brain Research, 2024 - Elsevier
Background Antidepressant treatment effects are strongly heritable and have substantial
effects on brain function and structure, but the underlying mechanisms are still poorly …

Effects of Meranzin Hydrate On the LncRNA–miRNA–mRNA Regulatory Network in the Hippocampus of a Rat Model of Depression

K Nie, L Liu, L Peng, M Zhang, C Zhang, B **ao… - Journal of Molecular …, 2022 - Springer
Meranzin hydrate (MH) is a frequently used antidepressant drug in China; however it
underlying mechanism remains unknown. In this study, we aimed to explore whether MH …

[KNJIGA][B] The science of lithium

FR Spellman - 2023 - taylorfrancis.com
The use of lithium is increasing at breathtaking speed and is currently changing key
industries and the way people live. Lithium is used in an ever-growing number of electric …

[HTML][HTML] Gastric serotonin biosynthesis and its functional role in L-arginine-induced gastric proton secretion

AK Holik, K Schweiger, V Stoeger, B Lieder… - International journal of …, 2021 - mdpi.com
Among mammals, serotonin is predominantly found in the gastrointestinal tract, where it has
been shown to participate in pathway-regulating satiation. For the stomach, vascular …