Background: The current focus in multiple sclerosis (MS) is on early diagnosis and drug
intervention, with a view to modifying disease progression. Consequently, healthcare costs …

Objective: Studies on the relationship between depression and cognition on patients with
multiple sclerosis (MS) are inconsistent and it is not clear whether higher depression levels …

Objective: Previous research suggests that everyday discrimination is associated with worse
concomitant performance in several cognitive domains, as well as faster subsequent …

Objective: To identify evidence in the literature presenting the economic and humanistic
(based on health state utility values [HSUVs]) burden of multiple sclerosis (MS) and report …

Depression and anxiety are common among persons with multiple sclerosis (MS), and both
negatively affect functional status. However, studies rarely account for overlap in depressive …

Background: Cognitive impairment is common in multiple sclerosis (MS) and can manifest
early in the disease process, sometimes as early as the first demyelinating event. However …

Background: Cognition is affected by relapses in persons with multiple sclerosis (PwMS), yet
the Expanded Disability Status Scale (EDSS) does not readily detect cognitive changes …

Background Exercise is known to prevent cognitive decline. Sleep quality and depression
symptoms, which are associated with processing speed, are considered as common …

Background: People with multiple sclerosis (MS) experience myriad symptoms that
negatively affect their quality of life. Despite significant progress in rehabilitation strategies …

Purpose The purpose of this study was to investigate the impact of the type of data capture
on the time and help needed for collecting patient-reported outcomes as well as on the …