Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

[HTML][HTML] Peptides and peptidomimetics for antimicrobial drug design

B Mojsoska, H Jenssen - Pharmaceuticals, 2015 - mdpi.com
The purpose of this paper is to introduce and highlight a few classes of traditional
antimicrobial peptides with a focus on structure-activity relationship studies. After first …

Transmembrane ion channels formed by a Star of David [2] catenane and a molecular pentafoil knot

DP August, S Borsley, SL Cockroft… - Journal of the …, 2020 - ACS Publications
A (FeII) 6-coordinated triply interlocked (“Star of David”)[2] catenane (612 link) and a (FeII) 5-
coordinated pentafoil (51) knot are found to selectively transport anions across phospholipid …

[HTML][HTML] Peptaibols: Diversity, bioactivity, and biosynthesis

X Hou, R Sun, Y Feng, R Zhang, T Zhu, Q Che… - Engineering …, 2022 - Elsevier
Peptaibols are a large family of linear, amphipathic polypeptides consisting of 5-20 amino
acid residues generated from the fungal nonribosomal peptide synthetase (NRPS) pathway …

The SMART model: Soft Membranes Adapt and Respond, also Transiently, in the presence of antimicrobial peptides

B Bechinger - Journal of Peptide Science, 2015 - Wiley Online Library
Biophysical and structural studies of peptide–lipid interactions, peptide topology and
dynamics have changed our view on how antimicrobial peptides insert and interact with …

Recent applications of synchrotron radiation and neutrons in the study of soft matter

T Narayanan, H Wacklin, O Konovalov… - Crystallography …, 2017 - Taylor & Francis
The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …

Polymyxin B loosens lipopolysaccharide bilayer but stiffens phospholipid bilayer

L Fu, M Wan, S Zhang, L Gao, W Fang - Biophysical journal, 2020 - cell.com
Multidrug-resistant Gram-negative bacteria have increased the prevalence of a variety of
serious diseases in modern times. Polymyxins are used as the last-line therapeutic options …

New insights into the echinocandins and other fungal non-ribosomal peptides and peptaibiotics

G Bills, Y Li, L Chen, Q Yue, XM Niu, Z An - Natural product reports, 2014 - pubs.rsc.org
Covering: 2009 to Spring 2014 Non-ribosomal peptide synthetases (NRPSs) are a primary
modality for fungal peptidic natural product assembly and are responsible for some of the …

Length-Dependent Formation of Transmembrane Pores by 310-Helical α-Aminoisobutyric Acid Foldamers

JE Jones, V Diemer, C Adam, J Raftery… - Journal of the …, 2016 - ACS Publications
The synthetic biology toolbox lacks extendable and conformationally controllable yet easy-to-
synthesize building blocks that are long enough to span membranes. To meet this need, an …

Enhanced EGFR targeting activity of plasmonic nanostructures with engineered GE11 peptide

F Biscaglia, S Rajendran, P Conflitti… - Advanced …, 2017 - Wiley Online Library
Plasmonic nanostructures show important properties for biotechnological applications, but
they have to be guided on the target for exploiting their potentialities. Antibodies are the …