Sperm motility is generated by a highly organized, microtubule-based structure, called the
axoneme, which is constructed from approximately 250 proteins. Recent studies have …

Sperm motility is necessary for the transport of male DNA to eggs in species with both
external and internal fertilization. Flagella comprise several proteins for generating and …

Dr. Harris has played a major role in the development of this organism as a model system.
Her previous version of the Chlamydomonas Sourcebook which published in 1989, has …

Dynein-decorated doublet microtubules (DMTs) are critical components of the oscillatory
molecular machine of cilia, the axoneme, and have luminal surfaces patterned periodically …

The axoneme of motile cilia is the largest macromolecular machine of eukaryotic cells. In
humans, impaired axoneme function causes a range of ciliopathies. Axoneme assembly …

Axonemal dyneins are tethered to doublet microtubules inside cilia to drive ciliary beating, a
process critical for cellular motility and extracellular fluid flow. Axonemal dyneins are …

A diverse family of cytoskeletal dynein motors powers various cellular transport systems,
including axonemal dyneins generating the force for ciliary and flagellar beating essential to …

Axonemal dyneins form the inner and outer rows of arms associated with the doublet
microtubules of motile cilia. These enzymes convert the chemical energy released from …

Ciliary motility is crucial for the development and health of many organisms. Motility depends
on the coordinated activity of multiple dynein motors arranged in a precise pattern on the …

The role of the eukaryotic flagellum in cell motility is well established but its importance in
many other aspects of cell biology, from cell signalling to developmental regulation, is …