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Insertion sequences
Insertion sequences (ISs) constitute an important component of most bacterial genomes.
Over 500 individual ISs have been described in the literature to date, and many more are …
Over 500 individual ISs have been described in the literature to date, and many more are …
Transposable elements in Drosophila
Transposable elements (TEs) are mobile genetic elements that can mobilize within host
genomes. As TEs comprise more than 40% of the human genome and are linked to …
genomes. As TEs comprise more than 40% of the human genome and are linked to …
Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
Mitochondria contain their own genomes that, unlike nuclear genomes, are inherited only in
the maternal line. Owing to a high mutation rate and low levels of recombination of …
the maternal line. Owing to a high mutation rate and low levels of recombination of …
First records of the potential pest species Drosophila suzukii (Diptera: Drosophilidae) in Europe
G Calabria, J Máca, G Bächli, L Serra… - Journal of Applied …, 2012 - Wiley Online Library
Drosophila suzukii ovoposits and feeds on healthy fruits, unlike most other Drosophila
species. It has been traditionally reported from Asia, but in the last 2 years it has been …
species. It has been traditionally reported from Asia, but in the last 2 years it has been …
Mutation of a mutL Homolog in Hereditary Colon Cancer
N Papadopoulos, NC Nicolaides, YF Wei, SM Ruben… - Science, 1994 - science.org
Some cases of hereditary nonpolyposis colorectal cancer (HNPCC) are due to alterations in
a mutS-related mismatch repair gene. A search of a large database of expressed sequence …
a mutS-related mismatch repair gene. A search of a large database of expressed sequence …
Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium
Background RNA interference (RNAi) is a highly conserved cellular mechanism. In some
organisms, such as Caenorhabditis elegans, the RNAi response can be transmitted …
organisms, such as Caenorhabditis elegans, the RNAi response can be transmitted …
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms
We previously reported a CRISPR-mediated knock-in strategy into introns of Drosophila
genes, generating an attP-FRT-SA-T2A-GAL4-polyA-3XP3-EGFP-FRT-attP transgenic …
genes, generating an attP-FRT-SA-T2A-GAL4-polyA-3XP3-EGFP-FRT-attP transgenic …
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
A major obstacle to creating precisely expressed transgenes lies in the epigenetic effects of
the host chromatin that surrounds them. Here we present a strategy to overcome this …
the host chromatin that surrounds them. Here we present a strategy to overcome this …
Drosophila S6 Kinase: A Regulator of Cell Size
Cell proliferation requires cell growth; that is, cells only divide after they reach a critical size.
However, the mechanisms by which cells grow and maintain their appropriate size have …
However, the mechanisms by which cells grow and maintain their appropriate size have …
Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy models
De novo point mutations in GNAO1, gene encoding the major neuronal G protein Gαo, have
recently emerged in patients with pediatric encephalopathy having motor, developmental …
recently emerged in patients with pediatric encephalopathy having motor, developmental …