Objectives The aim of the present systematic review was to offer a timeline of the events
taking place during orthodontic tooth movement (OTM). Materials and methods Electronic …

Background&objectives Mechanical forces applied during an orthodontic tooth movement
(OTM) propel several biochemical and molecular responses in the periodontal ligament and …

Background The balance between osteoblastic and osteoclastic activity is critical in
orthodontic tooth movement (OTM). Mesenchymal stem cells (MSCs) play an important role …

Orthodontic tooth movement (OTM) is induced by biomechanical stimuli and facilitated by
periodontal tissue remodeling, where multiple immune cells participate in this progression. It …

Background Tooth movement is a unique bone remodeling process induced by mechanical
stimulation. Macrophages are important in mediating inflammatory processes during …

The bone remodeling process in response to orthodontic forces requires the activity of
osteoclasts to allow teeth to move in the direction of the force applied. Receptor activator of …

Macrophages play a crucial role in inflammatory-mediated bone loss. Orthodontic tooth
movement (OTM) is associated with inflammatory bone remodeling. However, whether and …

Autophagy, a lysosomal degradation pathway, serves as a protective cellular mechanism in
maintaining cell and tissue homeostasis under mechanical stimulation. As the …

Osteogenic differentiation and bone formation are tightly regulated by several factors,
including microRNAs (miRNAs). However, miRNA expression patterns and function during …

Despite the successful clinical application of titanium (Ti) as a biomaterial, the exact cellular
and molecular mechanisms responsible for Ti osseointegration remains unclear, especially …