Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Remodeling of the maternal uterine vasculature during pregnancy is a unique
cardiovascular process that occurs in the adult and results in significant structural and …

Pre-eclampsia is a placental disorder that affects 3–5% of all pregnancies and is a leading
cause of maternal and fetal morbidity worldwide 1, 2. With no drug available to slow disease …

Successful pregnancy and long-term, post-natal maternal and offspring cardiac, vascular
and metabolic health require key maternal cardiovascular adaptations over gestation. Within …

Successful pregnancy and reproduction are dependent on adequate uterine blood flow,
placental perfusion, and vascular responsivity to fetal demands. The ability to support …

The use of nanoparticles (NPs) to deliver therapeutics to reproductive organs is an emerging
approach to safely and effectively treat mothers and babies facing pregnancy complications …

The placenta performs a wide range of physiological functions; insufficiencies in these
functions may result in a variety of severe prenatal and postnatal syndromes with long-term …

Caffeine is commonly consumed by pregnant women to avoid fatigue or as a habit.
However, it is not clearly determined its side effects to the conceptuses. This study evaluated …

Pregnancy is a unique condition, and the vascular processes that are required for this
undertaking are both complex and extensive. In this review, we discuss the vascular …

Although expansive remodeling of the maternal uterine circulation during pregnancy is
essential for maintaining uteroplacental perfusion and normal fetal growth, the underlying …