The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Sleep is critical for diverse aspects of brain function in animals ranging from invertebrates to
humans. Powerful genetic tools in the fruit fly Drosophila melanogaster have identified—at …

In the last three decades the two‐process model of sleep regulation has served as a major
conceptual framework in sleep research. It has been applied widely in studies on fatigue …

Sleep is homeostatically regulated with sleep pressure accumulating with the increasing
duration of prior wakefulness. Yet, a clear understanding of the molecular components of the …

The recent development of automatised methods to score various behaviours on a large
number of animals provides biologists with an unprecedented set of tools to decipher these …

To survive adverse environments, many animals enter a dormant state such as hibernation,
dauer, or diapause. Various Drosophila species undergo adult reproductive diapause in …

Sleep is a dynamic process comprising multiple stages, each associated with distinct
electrophysiological properties and potentially serving different functions. While these …

The dynamic nature of sleep in many animals suggests distinct stages that serve different
functions. Genetic sleep induction methods in animal models provide a powerful way to …

Identifying different sleep stages in humans and other mammals has traditionally relied on
electroencephalograms. Such an approach is not feasible in certain animals such as …

As one of the most successful intracellular symbiotic bacteria, Wolbachia can infect many
arthropods and nematodes. Wolbachia infection usually affects the reproduction of their …