Metabolic engineering advances and prospects for amino acid production

VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

A review on hydrothermal liquefaction of algal biomass on process parameters, purification and applications

SR Ravichandran, CD Venkatachalam, M Sengottian… - Fuel, 2022 - Elsevier
Algae, a potential biomass feedstock with a faster growth rate and capability of greenhouse
gas absorption, mitigates the limitations of the first-and second-generation feedstock in bio …

Microbial production of gamma-aminobutyric acid: applications, state-of-the-art achievements, and future perspectives

H Luo, Z Liu, F **e, M Bilal, L Liu, R Yang… - Critical Reviews in …, 2021 - Taylor & Francis
Gamma-aminobutyric acid (GABA) is an important non-protein amino acid with wide-ranging
applications. Currently, GABA can be produced by a variety of methods, including chemical …

Recent advances in the biosynthesis and industrial biotechnology of Gamma-amino butyric acid

RB Milon, P Hu, X Zhang, X Hu, L Ren - Bioresources and Bioprocessing, 2024 - Springer
Abstract GABA (Gamma-aminobutyric acid), a crucial neurotransmitter in the central nervous
system, has gained significant attention in recent years due to its extensive benefits for …

[HTML][HTML] Stevioside attenuates insulin resistance in skeletal muscle by facilitating IR/IRS-1/Akt/GLUT 4 signaling pathways: an in vivo and in silico approach

A Deenadayalan, V Subramanian, V Paramasivan… - Molecules, 2021 - mdpi.com
Type-2 diabetes mellitus (T2DM), the leading global health burden of this century majorly
develops due to obesity and hyperglycemia-induced oxidative stress in skeletal muscles …

Effect of DR1558, a Deinococcus radiodurans response regulator, on the production of GABA in the recombinant Escherichia coli under low pH conditions

S Park, YJ Sohn, SJ Park, J Choi - Microbial Cell Factories, 2020 - Springer
Background Gamma aminobutyric acid (GABA) is an important platform chemical, which has
been used as a food additive and drug. Additionally, GABA is a precursor of 2-pyrrolidone …

Production of γ-aminobutyric acid in Escherichia coli by engineering MSG pathway

P Yu, K Chen, X Huang, X Wang… - Preparative Biochemistry …, 2018 - Taylor & Francis
The compound γ-aminobutyric acid (GABA) has many important physiological functions. The
effect of glutamate decarboxylases and the glutamate/GABA antiporter on GABA production …

Whole-cell display of Pyrococcus horikoshii glutamate decarboxylase in Escherichia coli for high-titer extracellular gamma-aminobutyric acid production

S Somasundaram, J Jeong… - Journal of Industrial …, 2021 - academic.oup.com
We investigated the effect of cell-surface display of glutamate decarboxylase (GadB) on
gamma-aminobutyric acid (GABA) production in recombinant Escherichia coli. We …

Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach

R Govindan, M El-Sherbiny, KMM Ibraheem… - Molecules, 2022 - mdpi.com
Osteoporosis is a skeletal disease that is both systemic and silent characterized by an
unbalanced activity of bone remodeling leading to bone loss. Rising evidences demonstrate …

Cell surface display of Neurospora crassa glutamate decarboxylase on Escherichia coli for extracellular Gamma-aminobutyric acid production from high cell density …

S Somasundaram, J Jeong, SH Hong - Biochemical Engineering Journal, 2021 - Elsevier
GABA is produced from the decarboxylation of glutamate by glutamate decarboxylase
enzyme (GadB). Various hetrologous GadB enzymes has been indentified and introduced in …