Heme oxygenase (HO)-1 is known to metabolize heme into biliverdin/bilirubin, carbon
monoxide, and ferrous iron, and it has been suggested to demonstrate cytoprotective effects …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

Mesenchymal stem cells (MSCs) protect tissues against cell death induced by
ischemia/reperfusion insults. This therapeutic effect seems to be controlled by physiological …

Carbon monoxide (CO) is generated in living organisms during the degradation of heme by
the enzyme heme oxygenase, which exists in constitutive (HO-2 and HO-3) and inducible …

Background Nanoparticles possess exceptional physical and chemical properties which led
to rapid commercialisation. Silver nanoparticles (Ag-np) are among the most …

Hearing loss caused by exposure to recreational and occupational noise remains a
worldwide disabling condition and dysregulation of redox homeostasis is the hallmark of …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Our review aims to examine the cellular and molecular mechanisms of cardiovascular
protection of green tea polyphenols, particularly epigallocatechin gallate (EGCG), which …

1 The enzyme heme oxygenase‐1 (HO‐1) is a cytoprotective and anti‐inflammatory protein
that degrades heme to produce biliverdin/bilirubin, ferrous iron and carbon monoxide (CO) …

Biliverdin and bilirubin are reducing species and hence potential antioxidants formed by the
action of heme oxygenase and biliverdin reductase. Indeed, there is increasing evidence for …