Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing research reviews, 2021‏ - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Immunology of aging: the birth of inflammaging

T Fulop, A Larbi, G Pawelec, A Khalil, AA Cohen… - Clinical reviews in …, 2021‏ - Springer
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

[HTML][HTML] The interplay between the gut microbiome and the immune system in the context of infectious diseases throughout life and the role of nutrition in optimizing …

SP Wiertsema, J van Bergenhenegouwen, J Garssen… - Nutrients, 2021‏ - mdpi.com
Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …

The aging gut microbiome and its impact on host immunity

N Bosco, M Noti - Genes & Immunity, 2021‏ - nature.com
The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

Nutrition, immunity and COVID-19

PC Calder - BMJ nutrition, prevention & health, 2020‏ - pmc.ncbi.nlm.nih.gov
The immune system protects the host from pathogenic organisms (bacteria, viruses, fungi,
parasites). To deal with this array of threats, the immune system has evolved to include a …

Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health

A Mukherjee, C Lordan, RP Ross, PD Cotter - Gut microbes, 2020‏ - Taylor & Francis
Over the last two decades our understanding of the gut microbiota and its contribution to
health and disease has been transformed. Among a new 'generation'of potentially beneficial …

Post-COVID-19 acute sarcopenia: physiopathology and management

K Piotrowicz, J Gąsowski, JP Michel… - Aging clinical and …, 2021‏ - Springer
In this review, we discuss the pathophysiologic and management aspects of acute
sarcopenia in relation to SARS-CoV-2 infection. COVID-19 is as a multi-organ infectious …

Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism

J Gao, K Xu, H Liu, G Liu, M Bai, C Peng… - Frontiers in cellular and …, 2018‏ - frontiersin.org
The gut microbiota influences the health of the host, especially with regard to gut immune
homeostasis and the intestinal immune response. In addition to serving as a nutrient …

Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?

NA Duggal, G Niemiro, SDR Harridge… - Nature Reviews …, 2019‏ - nature.com
Remodelling of the immune system with age—immunosenescence—is a substantial
contributor to poor health in older adults, with increasing risk of infections, cancer and …

Introduction to the human gut microbiota

E Thursby, N Juge - Biochemical journal, 2017‏ - portlandpress.com
The human gastrointestinal (GI) tract harbours a complex and dynamic population of
microorganisms, the gut microbiota, which exert a marked influence on the host during …