[PDF][PDF] Hormones and the hippocampus
R Lathe - Journal of Endocrinology, 2001 - researchgate.net
Hippocampal lesions produce memory deficits, but the exact function of the hippocampus
remains obscure. Evidence is presented that its role in memory may be ancillary to …
remains obscure. Evidence is presented that its role in memory may be ancillary to …
Proneural bHLH genes in development and disease
Proneural genes encode evolutionarily conserved basic-helix–loop–helix transcription
factors. In Drosophila, proneural genes are required and sufficient to confer a neural identity …
factors. In Drosophila, proneural genes are required and sufficient to confer a neural identity …
The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms
The basic helix-loop-helix (bHLH) transcription factor genes Hand1 and Mash2 are essential
for placental development in mice. Hand1 promotes differentiation of trophoblast giant cells …
for placental development in mice. Hand1 promotes differentiation of trophoblast giant cells …
Differential interactions of Id proteins with basic-helix-loop-helix transcription factors
Dimerization of three Id proteins (Id1, Id2, and Id3) with the four class AE proteins (E12, E47,
E2-2, and HEB) and two groups of class B proteins, the myogenic regulatory factors (MRFs …
E2-2, and HEB) and two groups of class B proteins, the myogenic regulatory factors (MRFs …
The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors
A Flora, JJ Garcia, C Thaller… - Proceedings of the …, 2007 - National Acad Sciences
Proneural factors represent< 10 transcriptional regulators required for specifying all of the
different neurons of the mammalian nervous system. The mechanisms by which such a …
different neurons of the mammalian nervous system. The mechanisms by which such a …
Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis
Y Jen, K Manova, R Benezra - Developmental dynamics: an …, 1997 - Wiley Online Library
We have performed a detailed comparative in situ hybridization analysis to examine the
patterns of expression of all the members of the Id gene family (Id1–4) during marine …
patterns of expression of all the members of the Id gene family (Id1–4) during marine …
Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5′ exon usage and splicing
Background Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous
class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While …
class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While …
Severe mental retardation with breathing abnormalities (Pitt–Hopkins syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor TCF4
A Brockschmidt, U Todt, S Ryu… - Human molecular …, 2007 - academic.oup.com
Pitt–Hopkins syndrome (PHS) is a rare syndromic mental disorder, which is mainly
characterized by severe motor and mental retardation including absent language …
characterized by severe motor and mental retardation including absent language …
Pitt–Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative …
Transcription factor TCF4 (alias ITF2, SEF2 or E2-2) is a broadly expressed basic helix–loop–
helix (bHLH) protein that functions as a homo-or heterodimer. Missense, nonsense, frame …
helix (bHLH) protein that functions as a homo-or heterodimer. Missense, nonsense, frame …
Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective
Schizophrenia is a genetically complex disease considered to have a neurodevelopmental
pathogenesis and defined by a broad spectrum of positive and negative symptoms as well …
pathogenesis and defined by a broad spectrum of positive and negative symptoms as well …