Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Currently, cancer ranks as the second leading cause of death worldwide, and at the same
time, the burden of cancer continues to increase. The underlying molecular pathways …

Medicinal plants are being used for therapeutic purposes since the dawn of human
civilization. The therapeutic efficacy of medicinal plants is due to the presence of wide range …

In recent years, natural compounds have received considerable attention in preventing and
curing most dreadful diseases including cancer. The reason behind the use of natural …

Objective: Docetaxel (DTX) remains the only effective drug for prolonging survival and
improving quality of life of metastatic castration-resistant prostate cancer (mCRPC) patients …

The endoplasmic reticulum (ER), a cellular organelle with multiple functions, plays an
important role in several biological processes including protein folding, secretion, lipid …

Background: Research over the past several years has developed many mono-targeted
therapies for the prevention and treatment of cancer, but it still remains one of the fatal …

Background Curcumin induces apoptosis and autophagy in different cancer cells. Moreover,
chemical and biological experiments have evidenced that curcumin is a biologically active …