Abstract Purpose of Review Adenoid cystic carcinoma (ACC) is a rare and heterogeneous
malignancy of secretory glands. Recurrence after curative-intent treatment is common, and …

Quercetin, one of the most common natural flavonoids, has been reported to possess
significant anti-tumor activities both in vitro and in vivo. The present study was to investigate …

Adenoid cystic carcinoma of salivary glands is a rare adenocarcinoma and has been placed
in “high-risk” category as poor long-term prognosis. The purpose of this study was to …

Background PI 3K–AKT–mTOR signaling pathway is associated with several cellular
functions and is frequently changed in several malignancies. The aim of this study was to …

We hypothesized that next-generation sequencing could reveal actionable genomic
alterations (GAs) and potentially expand treatment options for patients with advanced …

Background Understanding cell signaling pathways that contribute to metastatic colon
cancer is critical to risk stratification in the era of personalized therapeutics. Here, we dissect …

Purpose: Conventional chemotherapy has modest efficacy in advanced adenoid cystic
carcinomas (ACC). Tumor recurrence is a major challenge in the management of ACC …

We recently demonstrated that Semaphorin 3 A (Sema3A), the expression of which is
negatively regulated by Wnt/β-catenin signaling, promotes odontogenic epithelial cell …

Salivary gland carcinomas encompass a wide spectrum of histological entities. To identify
candidate therapeutic targets and innovative treatment options for these carcinomas, we …

Restricted availability of cell and animal models is a rate-limiting step for investigation of
salivary gland neoplasm pathophysiology and therapeutic response. Conditionally …