Optobiochemical control of protein activities allows the investigation of protein functions in
living cells with high spatiotemporal resolution. Over the last two decades, numerous natural …

Inspired by natural transcription factors (TFs), researchers have explored the potential of
artificial peptides for the recognition of specific DNA sequences, develo** increasingly …

The precise spatiotemporal regulation of protein synthesis is essential for many complex
biological processes such as memory formation, embryonic development, and tumor …

Photoactive yellow proteins (PYPs) make up a diverse class of blue-light-absorbing bacterial
photoreceptors. Electronic excitation of the p-coumaric acid chromophore covalently bound …

Myosins play countless critical roles in the cell, each requiring it to be activated at a specific
location and time. To control myosin VI with this specificity, we created an optogenetic tool …

We report the design and characterization of photoactive yellow protein (PYP)–blue
fluorescent protein (mTagBFP) fusion constructs that permit the direct assay of reconstitution …

Photo-induced structural rearrangements of chromophore-containing proteins are essential
for various light-dependent signaling pathways and optogenetic applications. Ultrafast …

Based on a bacterial blue light photoreceptor, photoactive yellow protein (PYP), we have
developed a photoresponsive protein module, Hpg5‐PYP, bearing five alkynyl groups as …

Photoreceptors control biological functions by harnessing changes in the chemical structure
of the protein in response to light. The Photoactive Yellow Protein (PYP) family of …

Proteins are a remarkable class of macromolecules. With a limited number of building
blocks, amino acids, they adopt an incredible diversity of three dimensional structures, each …