Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …

Liquid biopsy is becoming a very popular sample obtaining procedure, replacing the
invasive sampling methods for the diagnostic protocols. The advantages of this method …

A radioimmunoassay for ng quantities of DNA was developed.[125I] Iododeoxyuridine-
labeled DNA was used as the antigen, and the serum of a lupus erythematosus patient …

Increased levels of DNA fragments have frequently been found in the blood plasma of
cancer patients. Published data suggest that only a fraction of the DNA in blood plasma is …

Small amounts of free DNA circulate in both healthy and diseased human plasma/serum,
and increased concentrations of DNA are present in the plasma of cancer patients …

Previous studies showed that patients with neoplasms of various types and origins have
abnormally high concentration of DNA in their serum. The current work compares circulating …

The presence of small amounts of tumor DNA in cell free DNA (CFDNA) circulating in the
plasma or serum of cancer patients was first demonstrated 30 years ago. Since then, overall …

Aberrant DNA methylation has shown promise as a biomarker for the early detection of
cancer. To discover novel genes frequently methylated at an early stage in colorectal cancer …

Background: Evaluation of tumor-specific circulating DNA in plasma/serum is a promising
noninvasive diagnostic and prognostic tool requiring only a blood sample, which …

BACKGROUND: The importance of circulating DNA has been recognized since the
detection of mutated oncogene products in cancer patients; however, there is little …