Aptamer-based point-of-care-testing for small molecule targets: From aptamers to aptasensors, devices and applications

L Zhao, L Li, Y Zhao, C Zhu, R Yang, M Fang… - TrAC Trends in Analytical …, 2023 - Elsevier
Point-of-care testing (POCT) represented the diagnosis performing at or near patient located
site, has extended applications in healthcare, environmental safety, or food quality with low …

CRISPR/Cas-engineered technology: Innovative approach for biosensor development

TS Zavvar, Z Khoshbin, M Ramezani… - Biosensors and …, 2022 - Elsevier
On-site and real-time clinical monitoring have been progressed dramatically by integrating
biosensor science with portable digital electronic technology. Clustered regularly …

Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control

Z Khoshbin, M Moeenfard, K Abnous, SM Taghdisi - Food Chemistry, 2023 - Elsevier
A simple aptasensor is embedded in the internal surface of a micropipette tip as the
aptasensor substrate for the label-free monitoring of acrylamide. The aptasensor is based on …

A ternary heterostructure aptasensor based on metal-organic framework and polydopamine nanoparticles for fluorescent detection of sulfamethazine

N Liang, B Shi, X Hu, W Li, X Huang, Z Li, X Zhang… - Food Chemistry, 2024 - Elsevier
Residue of sulfamethazine (SMZ), a typical short-acting drug to prevent bacterial infections,
in food is a threat to human health. A ternary heterogeneous metal-organic framework hybrid …

An electrochemical aptasensor based on exonuclease III-assisted signal amplification coupled with CRISPR-Cas12a for ochratoxin A detection

C Wu, X Wang, L Guo, X Huang, L Wu, H Huang - Food Control, 2023 - Elsevier
Selective and sensitive determination of ochratoxin A (OTA) is critical due to its high toxicity
and wide distribution. Here, a neoteric electrochemical biosensor based on an exonuclease …

An ultrasensitive liquid crystal aptasensing chip assisted by three-way junction DNA pockets for acrylamide detection in food samples

Z Khoshbin, F Mohammadi, M Moeenfard… - Journal of Hazardous …, 2024 - Elsevier
Acrylamide, an unsaturated amide found in heat-processed foods, poses serious risks to
human health due to its neurotoxicity, carcinogenicity, and genotoxicity. This highlights the …

An ultrasensitive electrochemical aptasensor based on Pd@ PCN-222 as a signal probe coupled with exonuclease III-assisted cycling amplification for the detection of …

C Wu, X Wu, F Hou, L Wu, G Liu - Food Control, 2022 - Elsevier
An ultrasensitive electrochemical aptasensor was established based on metalloporphyrin
metal organic frameworks (Pd@ PCN-222) with peroxidase-like activity and exonuclease III …

An ultra-sensitive dual-responsive aptasensor with combination of liquid crystal and intercalating dye molecules: A food toxin case study

Z Khoshbin, K Abnous, SM Taghdisi, A Verdian… - Food Chemistry, 2022 - Elsevier
Herein, a label-free aptasensor was designed through forming a double-stranded DNA
skeleton on the glass substrate for ultrasensitive quantification of ochratoxin A (OTA) as a …

A tag-free fluorescent aptasensor for tobramycin detection using a hybridization of three aptamer strands and SYBR Green I dye

H Zahraee, Z Khoshbin, M Ramezani… - … Acta Part A: Molecular …, 2023 - Elsevier
In this study, a sensitive fluorescent method is designed to detect tobramycin (TOB) drug
applying a hybrid structure of three aptamer strands and SYBR Green I (SGI) fluorescent dye …