Abstract Y-box-binding protein 1 (YB-1) is a DNA/RNA binding protein increasingly
implicated in the regulation of cancer cell biology. Normally located in the cytoplasm …

Aims To overcome radioresistant cancer cells, clinically relevant radioresistant (CRR) cells
were established. To maintain their radioresistance, CRR cells were exposed 2 Gy/day of X …

Multifunctional Y-box binding protein-1 (YB-1) is highly expressed in different human solid
tumors and is involved in various cellular processes. DNA damage is the major mechanism …

External beam radiotherapy (RT) is a leading first-line therapy for prostate cancer (PCa),
and, in recent years, significant advances have been accomplished. However, RT resistance …

Simple Summary Radiotherapy is an option for curing localized and locally advanced
prostate cancer. However, radioresistance can occur, determining treatment failure and poor …

Histomorphology and immunohistochemistry are the most common ways of cancer
classification in routine cancer diagnostics, but often reach their limits in determining the …

Radiotherapy is a widely used treatment modality for prostate cancer, but many patients
develop radioresistance over time, leading to treatment failure. Alterations in DNA repair …

The development of in vitro isogenic models of radioresistance through exposure to
fractionated radiation is an increasingly used approach to investigate the mechanisms of …

In recent years, scientific progress has led to the advancement of precision medicine, a
novel therapeutic strategy. For this purpose, molecular investigation of patient-derived …

Protein profiling of immune cells Page 1 Protein Profiling of Primary Human Samples for
Pathway Analysis and Patient Stratification Dissertation der Mathematisch-Naturwissenschaftlichen …