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Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers
Abstract The Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI),
formally established in 2009, aims to provide resources and facilitate research related to …
formally established in 2009, aims to provide resources and facilitate research related to …
A review of multivariate analyses in imaging genetics
Recent advances in neuroimaging technology and molecular genetics provide the unique
opportunity to investigate genetic influence on the variation of brain attributes. Since the year …
opportunity to investigate genetic influence on the variation of brain attributes. Since the year …
CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research
Abstract The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese
neuroimaging genetics cohort and aims to identify genetic and environmental factors and …
neuroimaging genetics cohort and aims to identify genetic and environmental factors and …
Epistasis analysis using multifactor dimensionality reduction
JH Moore, PC Andrews - Epistasis: Methods and Protocols, 2014 - Springer
Here we introduce the multifactor dimensionality reduction (MDR) methodology and
software package for detecting and characterizing epistasis in genetic association studies …
software package for detecting and characterizing epistasis in genetic association studies …
[HTML][HTML] Exploring genetic interactions in colombian women with polycystic ovarian syndrome: a study on SNP-SNP associations
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder with high
prevalence in women around the world. The identification of single-nucleotide …
prevalence in women around the world. The identification of single-nucleotide …
Sparse models for correlative and integrative analysis of imaging and genetic data
The development of advanced medical imaging technologies and high-throughput genomic
measurements has enhanced our ability to understand their interplay as well as their …
measurements has enhanced our ability to understand their interplay as well as their …
[HTML][HTML] Defining trajectories of linguistic, cognitive-communicative, and quality of life outcomes in aphasia: Longitudinal observational study protocol
Objective To describe the trajectories of linguistic, cognitive-communicative, and health-
related quality of life (HRQOL) outcomes after stroke in persons with aphasia. Design …
related quality of life (HRQOL) outcomes after stroke in persons with aphasia. Design …
[HTML][HTML] Incorporating epistasis interaction of genetic susceptibility single nucleotide polymorphisms in a lung cancer risk prediction model
Incorporation of genetic variants such as single nucleotide polymorphisms (SNPs) into risk
prediction models may account for a substantial fraction of attributable disease risk. Genetic …
prediction models may account for a substantial fraction of attributable disease risk. Genetic …
Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma
N Calbet‐Llopart, M Combalia, A Kiroglu… - British Journal of …, 2022 - academic.oup.com
Summary Background Hypomorphic MC1R variants are the most prevalent genetic
determinants of melanoma risk in the white population. However, the genetic background of …
determinants of melanoma risk in the white population. However, the genetic background of …
[HTML][HTML] What can machine learning approaches in genomics tell us about the molecular basis of amyotrophic lateral sclerosis?
Amyotrophic Lateral Sclerosis (ALS) is the most common late-onset motor neuron disorder,
but our current knowledge of the molecular mechanisms and pathways underlying this …
but our current knowledge of the molecular mechanisms and pathways underlying this …