Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers

L Shen, PM Thompson, SG Potkin, L Bertram… - Brain imaging and …, 2014 - Springer
Abstract The Genetics Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI),
formally established in 2009, aims to provide resources and facilitate research related to …

A review of multivariate analyses in imaging genetics

J Liu, VD Calhoun - Frontiers in neuroinformatics, 2014 - frontiersin.org
Recent advances in neuroimaging technology and molecular genetics provide the unique
opportunity to investigate genetic influence on the variation of brain attributes. Since the year …

CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research

Q Xu, L Guo, J Cheng, M Wang, Z Geng, W Zhu… - Molecular …, 2020 - nature.com
Abstract The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese
neuroimaging genetics cohort and aims to identify genetic and environmental factors and …

Epistasis analysis using multifactor dimensionality reduction

JH Moore, PC Andrews - Epistasis: Methods and Protocols, 2014 - Springer
Here we introduce the multifactor dimensionality reduction (MDR) methodology and
software package for detecting and characterizing epistasis in genetic association studies …

[HTML][HTML] Exploring genetic interactions in colombian women with polycystic ovarian syndrome: a study on SNP-SNP associations

MC Alarcón-Granados, GE Camargo-Villalba… - International Journal of …, 2024 - mdpi.com
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder with high
prevalence in women around the world. The identification of single-nucleotide …

Sparse models for correlative and integrative analysis of imaging and genetic data

D Lin, H Cao, VD Calhoun, YP Wang - Journal of neuroscience methods, 2014 - Elsevier
The development of advanced medical imaging technologies and high-throughput genomic
measurements has enhanced our ability to understand their interplay as well as their …

[HTML][HTML] Defining trajectories of linguistic, cognitive-communicative, and quality of life outcomes in aphasia: Longitudinal observational study protocol

LR Cherney, AJ Kozlowski, AA Domenighetti… - … Research and Clinical …, 2024 - Elsevier
Objective To describe the trajectories of linguistic, cognitive-communicative, and health-
related quality of life (HRQOL) outcomes after stroke in persons with aphasia. Design …

[HTML][HTML] Incorporating epistasis interaction of genetic susceptibility single nucleotide polymorphisms in a lung cancer risk prediction model

MW Marcus, OY Raji, SW Duffy… - International …, 2016 - spandidos-publications.com
Incorporation of genetic variants such as single nucleotide polymorphisms (SNPs) into risk
prediction models may account for a substantial fraction of attributable disease risk. Genetic …

Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma

N Calbet‐Llopart, M Combalia, A Kiroglu… - British Journal of …, 2022 - academic.oup.com
Summary Background Hypomorphic MC1R variants are the most prevalent genetic
determinants of melanoma risk in the white population. However, the genetic background of …

[HTML][HTML] What can machine learning approaches in genomics tell us about the molecular basis of amyotrophic lateral sclerosis?

C Vasilopoulou, AP Morris, G Giannakopoulos… - Journal of personalized …, 2020 - mdpi.com
Amyotrophic Lateral Sclerosis (ALS) is the most common late-onset motor neuron disorder,
but our current knowledge of the molecular mechanisms and pathways underlying this …