Sexual determination in zebrafish
D Aharon, FL Marlow - Cellular and Molecular Life Sciences, 2022 - Springer
Zebrafish have emerged as a major model organism to study vertebrate reproduction due to
their high fecundity and external development of eggs and embryos. The mechanisms …
their high fecundity and external development of eggs and embryos. The mechanisms …
mRNA translational specialization by RBPMS presets the competence for cardiac commitment in hESCs
The blueprints of develo** organs are preset at the early stages of embryogenesis.
Transcriptional and epigenetic mechanisms are proposed to preset developmental …
Transcriptional and epigenetic mechanisms are proposed to preset developmental …
Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences
RNA-binding proteins (RBPs) regulate RNA metabolism at multiple levels by affecting
splicing of nascent transcripts, RNA folding, base modification, transport, localization …
splicing of nascent transcripts, RNA folding, base modification, transport, localization …
Amyloid-Induced Neurodegeneration: A Comprehensive Review through Aggregomics Perception of Proteins in Health and Pathology
Amyloidosis of protein caused by fibrillation and aggregation are some of the most exciting
new edges not only in protein sciences but also in molecular medicines. The present review …
new edges not only in protein sciences but also in molecular medicines. The present review …
Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
M Yu, J Yi, Q Qiu, D Yao, J Li, J Yang, C Mi, L Zhou… - Cell Reports, 2023 - cell.com
Transfer RNA-derived fragments (tRFs) are a class of small non-coding regulatory RNAs that
are involved in the pathophysiology of many diseases. However, the role of tRFs in cancer …
are involved in the pathophysiology of many diseases. However, the role of tRFs in cancer …
L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes
CR Neil, SP Jeschonek, SE Cabral… - Molecular biology of …, 2021 - Am Soc Cell Biol
Ribonucleoprotein (RNP) granules are membraneless compartments within cells, formed by
phase separation, that function as regulatory hubs for diverse biological processes …
phase separation, that function as regulatory hubs for diverse biological processes …
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation
TT Gong, FH Liu, Q **ao, YZ Li, YF Wei, HL Xu… - Communications …, 2024 - nature.com
Platinum-based chemotherapy remains one of the major choices for treatment of ovarian
cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency …
cancer (OC). However, primary or acquired drug resistance severely impairs their efficiency …
RBPMS regulates cardiomyocyte contraction and cardiac function through RNA alternative splicing
Aims RNA binding proteins play essential roles in mediating RNA splicing and are key post-
transcriptional regulators in the heart. Our recent study demonstrated that RBPMS (RNA …
transcriptional regulators in the heart. Our recent study demonstrated that RBPMS (RNA …
RBPMS2 is a myocardial-enriched splicing regulator required for cardiac function
Background: RBPs (RNA-binding proteins) perform indispensable functions in the post-
transcriptional regulation of gene expression. Numerous RBPs have been implicated in …
transcriptional regulation of gene expression. Numerous RBPs have been implicated in …
Cell-type specific regulator RBPMS switches alternative splicing via higher-order oligomerization and heterotypic interactions with other splicing regulators
Y Yang, GC Lee, E Nakagaki-Silva… - Nucleic Acids …, 2023 - academic.oup.com
Alternative pre-mRNA splicing decisions are regulated by RNA binding proteins (RBPs) that
can activate or repress regulated splice sites. Repressive RBPs typically harness multivalent …
can activate or repress regulated splice sites. Repressive RBPs typically harness multivalent …