Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons

M Thouaye, I Yalcin - Pharmacology & therapeutics, 2023 - Elsevier
Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Trigeminal neuralgia: diagnosis and treatment

AK Allam, H Sharma, MB Larkin… - Neurologic …, 2023 - neurologic.theclinics.com
Trigeminal neuralgia (TN), the most common craniofacial neuralgia, results in intense,
debilitating facial pain and can profoundly affect quality of life. In this article, the authors …

[HTML][HTML] Medicating the environment? A critical review on the risks of carbamazepine, diclofenac and ibuprofen to aquatic organisms

NSP Batucan, LA Tremblay, GL Northcott… - Environmental …, 2022 - Elsevier
Pharmaceuticals are an important class of micropollutants within the freshwater
environment. There is sufficient evidence of their impacts on exposed biota to warrant further …

[HTML][HTML] The molecular basis and pathophysiology of trigeminal neuralgia

QL Chen, DI Yi, JNJ Perez, M Liu, SD Chang… - International journal of …, 2022 - mdpi.com
Trigeminal neuralgia (TN) is a complex orofacial pain syndrome characterized by the
paroxysmal onset of pain attacks in the trigeminal distribution. The underlying mechanism …

Gut microbiota modulation and its implications on neuropathic pain: a comprehensive literature review

A Corriero, M Giglio, F Inchingolo, A Moschetta… - Pain and Therapy, 2024 - Springer
Neuropathic pain (NP) is a chronic pain disorder arising from somatosensory nervous
system impairment. Extensive evidence supports the notion that the gut microbiota (GM) is …

Incidence of trigeminal neuralgia: a population‐based study in central Sweden

T Svedung Wettervik, D Snel… - … Journal of Pain, 2023 - Wiley Online Library
Background The primary aim of this observational study was to determine the incidence of
trigeminal neuralgia (TN) in a county in central Sweden. The secondary aim was to …

Trigeminal nerve stimulation: a current state-of-the-art review

K Powell, K Lin, W Tambo, AP Saavedra… - Bioelectronic …, 2023 - Springer
Nearly 5 decades ago, the effect of trigeminal nerve stimulation (TNS) on cerebral blood flow
was observed for the first time. This implication directly led to further investigations and …

[HTML][HTML] Chronic facial pain: Trigeminal neuralgia, persistent idiopathic facial pain, and myofascial pain syndrome—an evidence-based narrative review and …

R Gerwin - International journal of environmental research and …, 2020 - mdpi.com
Trigeminal neuralgia (TN), the most common form of severe facial pain, may be confused
with an ill-defined persistent idiopathic facial pain (PIFP). Facial pain is reviewed and a …

Cyclic tailor-made amino acids in the design of modern pharmaceuticals

J Liu, J Han, K Izawa, T Sato, S White… - European Journal of …, 2020 - Elsevier
Tailor-made AAs are indispensable components of modern medicinal chemistry and are
becoming increasingly prominent in new drugs. In fact, about 30% of small-molecule …

Intravenous lacosamide and phenytoin for the treatment of acute exacerbations of trigeminal neuralgia: A retrospective analysis of 144 cases

A Muñoz-Vendrell, S Teixidor, J Sala-Padró… - …, 2022 - journals.sagepub.com
Background Scant evidence is available on the use of intravenous pain treatment in acute
exacerbations of trigeminal neuralgia. The aim of this descriptive study was to evaluate the …